Evidence map›Paper›PMID 36081911›Full record

ArticleFrontiers in cell and developmental biology2022

Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy.

Binbin Huang, Lingling Jin, Luodan Zhang, Xiaolin Cui, Zhen Zhang, Yongqi Lu, Lujia Yu, Tonghui Ma, He Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. NMN/NADJournal of ovarian research · 2026
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Binbin HuangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Lingling JinDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Luodan ZhangDepartment of Nephrology, Anhui Provincial Children's Hospital, Hefei, Anhui, China.
Xiaolin CuiDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Zhen ZhangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Yongqi LuDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, MOE Key Laboratory of Population Health Across Life Cycle, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, Anhui, China.
Lujia YuDepartment of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, MOE Key Laboratory of Population Health Across Life Cycle, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei, Anhui, China.
Tonghui MaDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
He ZhangDepartment of Pathophysiology, College of Basic Medical Sciences, Dalian Medical University, Dalian, China.
Dalian Medical University · CNAnhui Medical University · CNAnhui Provincial Children's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aquaporin-8 (AQP8), a member of the aquaporin family, is strongly expressed in follicular granulosa cells, which could affect the hormone secretion level in females. AQP8, as a membrane protein, could mediate H

Indexed as

AQP8autophagyfollicular atresiagranulosa cellhydrogen peroxide

Identifiers

PMID36081911
PMCPMC9445271
OpenAlexW4292823698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.