Evidence map›Paper›PMID 36081814›Full record

ArticleJournal of traditional and complementary medicine2022

Antihistamine promotes electroacupuncture analgesia in healthy human subjects: A pilot study.

Yu-Chen Lee, Cheng-Hao Tu, Hsin-Yi Chung, Sih-Ting Luo, Yu-Ting Chu, Iona J MacDonald, Peddanna Kotha, Chien-Chen Huang, Hsien-Yuan Lane, Jaung-Geng Lin and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of traditional and complementary medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Yu-Chen LeeSchool of Chinese Medicine, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Cheng-Hao TuGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Hsin-Yi ChungGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Sih-Ting LuoGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Yu-Ting ChuGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Iona J MacDonaldGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Peddanna KothaGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Chien-Chen HuangDepartment of Traditional Chinese Medicine, An Nan Hospital, China Medical University, No.66, Sec. 2, Changhe Road, Tainan, 709204, Taiwan, ROC.
Hsien-Yuan LaneGraduate Institute of Biomedical Sciences, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Jaung-Geng LinSchool of Chinese Medicine, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
Yi-Hung ChenGraduate Institute of Acupuncture Science, China Medical University, No. 91, Hsueh-Shih Road, Taichung, 40402, Taiwan, ROC.
China Medical University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aim: We have previously reported that histamine H Experimental procedure: Forty healthy subjects aged 20-30 years were randomly allocated to 1 of 4 groups: (1) sham EA at acupoints Zusanli (ST36) and Yanglingquan (GB34) (sham EA; n = 10); (2) EA at ST36 and GB34 (n = 10); (3) EA at ST36 and GB34 plus low-dose DCPA (2 mg, n = 10); (4) EA at ST36 and GB34 plus high-dose DCPA (4 mg, n = 10). Before and after acupuncture treatment, pain thresholds were determined by transcutaneous electrical stimuli on the glabrous skin of the left upper arm. Results: After the acupuncture session, subjects in the EA plus high-dose DCPA group had a significantly higher pain threshold elevation compared with the other 3 study groups. The change from baseline in pain threshold in the EA plus high-dose DCPA group was significantly greater than the change in pain threshold with EA only, indicating that DCPA 4 mg facilitated EA analgesia. Conclusion: The results suggest that combining H

Indexed as

DexchlorpheniramineElectroacupunctureH1 receptor antagonistsPain thresholdPilot study

Identifiers

PMID36081814
PMCPMC9446023
OpenAlexW4224287055

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.