Evidence map›Paper›PMID 36081669›Full record

ArticleJournal of oncology2022

Significance of lncRNA CDKN2B-AS1 in Interventional Therapy of Liver Cancer and the Mechanism under Its Participation in Tumour Cell Growth via miR-199a-5p.

Lu Xu, Haotian Wu, Jianhua Pan, Zhiheng Chen, Linan Du

Open access · hybridAbstract read
In one paragraph

Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lu XuDepartment of Interventional Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, China.
Haotian WuDepartment of Interventional Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, China.
Jianhua PanDepartment of Interventional Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, China.
Zhiheng ChenDepartment of Interventional Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, China.
Linan DuDepartment of Interventional Ultrasound, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui 230000, China.ORCID https://orcid.org/0000-0002-1424-1281
Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Methods: Totally 34 LC patients admitted to our hospital between January 2020 and March 2021 (Obs group) and 32 healthy individuals over the same time span (Con group) were enrolled. CDKN2B-AS1 and miR-199a-5p in the two groups were PCR quantified, and their association and value for the diagnosis and therapy of LC were analyzed. In addition, purchased LC cells were adopted for Results: CDKN2B-AS1 in LC cases presented high expression and dropped after therapy ( Conclusion: With high expression in LC cases, CDKN2B-AS1 is implicated in the development and progression of LC by suppressing cell autophagy through targeting miR-199a-5p.

Identifiers

PMID36081669
PMCPMC9448535
OpenAlexW4293773675

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.