Evidence map›Paper›PMID 36081502›Full record

ReviewFrontiers in immunology2022

Research progress on the pathogenesis of Graves' ophthalmopathy: Based on immunity, noncoding RNA and exosomes.

Jingyi Zheng, Honghong Duan, Sufang You, Bo Liang, Yuping Chen, Huibin Huang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingyi ZhengThe Second Clinical Medical College of Fujian Medical University, Quanzhou, China.
Honghong DuanDepartment of Gynaecology and Obstetrics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Sufang YouThe Second Clinical Medical College of Fujian Medical University, Quanzhou, China.
Bo LiangDepartment of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Yuping ChenThe Second Clinical Medical College of Fujian Medical University, Quanzhou, China.
Huibin HuangDepartment of Endocrinology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Graves' ophthalmopathy (GO), also known as thyroid-associated ophthalmopathy, is a common potentially vision-threatening organ-specific autoimmune disease and the most common extrathyroidal manifestation of Graves' disease. It can happen to those who have hyperthyroidism or euthyroidism. At present, the pathogenesis of GO has not been fully elucidated, and the majority of clinical treatments are symptomatic. Therefore, we are eager to discover any new therapeutic strategies that target the etiology of GO. To provide fresh ideas for the creation of new therapeutic techniques, this study primarily discusses the research state and progress of GO-related pathogenesis from the perspectives of GO's cellular immunity, autoantigens, non-coding RNAs, and exosomes.

Indexed as

ExosomesGraves DiseaseGraves OphthalmopathyAutoantigensHumansRNA, UntranslatedAutoantigensRNA, Untranslatedautoantigenbiologicscellular immunityexosomesGraves’ ophthalmopathynoncoding RNA

Identifiers

PMID36081502
PMCPMC9445982

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.