Evidence map›Paper›PMID 36081405›Full record

ArticleInnovation in aging2022

Increased Social Support Reduces the Incidence of Motoric Cognitive Risk Syndrome.

Nicole Felix, Emmeline Ayers, Joe Verghese, Helena M Blumen

Open access · goldAbstract read
In one paragraph

Article in Innovation in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Social frailty and the incidence of motoric cognitive risk syndrome in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  10. Longitudinal Associations of Social Support and Gait Speed Decline in Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024
    Article
  11. Article
  12. Article
  13. Prodromal Motoric Cognitive Risk Syndrome and Everyday Function.Journal of Alzheimer's disease : JAD · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Nicole FelixDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.
Emmeline AyersDepartments of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA.
Joe VergheseDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0003-4252-2547
Helena M BlumenDepartment of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA.ORCID https://orcid.org/0000-0002-0275-6616
Albert Einstein College of Medicine · US

Funding

The biological underpinnings of Motoric Cognitive Risk syndrome: a multi-center studyR01AG057548 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI VERGHESE, JOE · 2020 to 2024
$8.0M
Trajectories and modifiable risk factors of brain, gait, and cognitive decline in aging and pre-dementiaR01AG062659 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI BLUMEN, HELENA M, MILMAN, SOFIYA · 2020 to 2024
$3.8M
Biological and neural mechanisms of fallsR01AG044007 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERGHESE, JOE · 2013 to 2017
$3.5M
Central Control of Mobility in AgingR01AG036921 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HOLTZER, ROEE · 2011 to 2015
$3.3M
The biological underpinnings of Motoric Cognitive Risk syndrome: a multi-center studyR56AG057548 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI VERGHESE, JOE · 2017 to 2017
$1.2M
NIA NIH HHS R01 AG036921NIA NIH HHS R01 AG044007NIA NIH HHS R01 AG057548NIA NIH HHS R01 AG062659NIA NIH HHS R56 AG057548
6 · The paper itself

Abstract

Background and Objectives: The motoric cognitive risk syndrome (MCR) is a predementia syndrome characterized by slow gait and cognitive complaint. The relationship between MCR and social support-a potentially modifiable risk factor of dementia-is currently unknown. The current study aimed to determine whether MCR incidence varies as a function of social support in aging. Research Design and Methods: We examined MCR incidence in 506 community-dwelling older adults ( Results: Over a median follow-up time of 2.5 years (range = 1-7 years), 38 participants (9.8%) developed MCR. Increased tangible support decreased the risk of MCR by 30% (aHR: 0.70, 95% CI: 0.53-0.92, Discussion and Implications: Higher levels of tangible social support, as well as overall social support, were associated with reduced risk for MCR in older adults. Increasing social support may be a promising avenue of intervention for reducing the risk of MCR, dementia, and other forms of cognitive decline.

Indexed as

Preclinical dementiaPredementiaSlow gaitSubjective cognitive complaint

Identifiers

PMID36081405
PMCPMC9447853
OpenAlexW4290660620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.