Evidence map›Paper›PMID 36080619›Full record

ArticlePolymers2022

Obtaining and Characterizing Composite Biomaterials of Animal Resources with Potential Applications in Regenerative Medicine.

Narcisa Babeanu, Nicoleta Radu, Cristina-Emanuela Enascuta, Elvira Alexandrescu, Mihaela Ganciarov, Mohammed Shaymaa Omar Mohammed, Ioana Raluca Suica-Bunghez, Raluca Senin, Magdalina Ursu, Marinela Bostan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Narcisa BabeanuFaculty of Biotechnology, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Boulevard, 011464 Bucharest, Romania.
Nicoleta RaduFaculty of Biotechnology, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Boulevard, 011464 Bucharest, Romania.ORCID 0000-0002-1106-0258
Cristina-Emanuela EnascutaBiotechnology, Bioresources and Analysis Departments, National Institute of Chemistry and Petrochemistry R&D of Bucharest, 202 Splaiul Independentei Street, 060021 Bucharest, Romania.ORCID 0000-0002-6234-3012
Elvira AlexandrescuBiotechnology, Bioresources and Analysis Departments, National Institute of Chemistry and Petrochemistry R&D of Bucharest, 202 Splaiul Independentei Street, 060021 Bucharest, Romania.
Mihaela GanciarovBiotechnology, Bioresources and Analysis Departments, National Institute of Chemistry and Petrochemistry R&D of Bucharest, 202 Splaiul Independentei Street, 060021 Bucharest, Romania.
Mohammed Shaymaa Omar MohammedFaculty of Biotechnology, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Boulevard, 011464 Bucharest, Romania.
Ioana Raluca Suica-BunghezBiotechnology, Bioresources and Analysis Departments, National Institute of Chemistry and Petrochemistry R&D of Bucharest, 202 Splaiul Independentei Street, 060021 Bucharest, Romania.
Raluca SeninBiotechnology, Bioresources and Analysis Departments, National Institute of Chemistry and Petrochemistry R&D of Bucharest, 202 Splaiul Independentei Street, 060021 Bucharest, Romania.
Magdalina UrsuFaculty of Biotechnology, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Boulevard, 011464 Bucharest, Romania.
Marinela BostanCenter of Immunology, Institute of Virology Stefan S. Nicolau, 285 Mihai Bravu Avenue, 030304 Bucharest, Romania.ORCID 0000-0003-3050-6486
University of Agronomic Sciences and Veterinary Medicine of Bucharest · RO

Funding

Ministry of Reseach Innovationa and Digitisation Romania 15PFE /2021
6 · The paper itself

Abstract

Raw materials, such as collagen and chitosan, obtained from by-products from the food industry (beef hides and crustacean exoskeletons), can be used to obtain collagen-chitosan composite biomaterials, with potential applications in regenerative medicine. Functionalization of these composite biomaterials is a possibility, thus, resulting in a molecule with potential applications in regenerative medicine, namely clotrimazole (a molecule with antibacterial, antifungal, and antitumor activity), at a mass ratio (collagen-chitosan-clotrimazole) of 1:1:0.1. This functionalized composite biomaterial has great potential for application in regenerative medicine, due to the following properties: (1) it is porous, and the pores formed are interconnected, due to the use of a mass ratio between collagen and chitosan of 1:1; (2) the size of the formed pores is between 500-50 μm; (3) between collagen and chitosan, hydrogen bonds are formed, which ensure the unity of composite biomaterial; (4) the functionalized bio-composite exhibits in vitro antimicrobial activity for

Indexed as

antimicrobialchitosanclotrimazolecollagencomposite biomaterials

Identifiers

PMID36080619
PMCPMC9460659
OpenAlexW4293770075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.