Evidence map›Paper›PMID 36080480›Full record

ArticleMolecules (Basel, Switzerland)2022

A Branched and Double Alpha-Gal-Bearing Synthetic Neoglycoprotein as a Biomarker for Chagas Disease.

Alba L Montoya, Elisa G Carvajal, Uriel Ortega-Rodriguez, Igor L Estevao, Roger A Ashmus, Sohan R Jankuru, Susana Portillo, Cameron C Ellis, Colin D Knight, Julio Alonso-Padilla and 11 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 4 countries.

Alba L MontoyaDepartment of Chemistry and Biochemistry, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Elisa G CarvajalDepartment of Chemistry and Biochemistry, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Uriel Ortega-RodriguezDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Igor L EstevaoDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Roger A AshmusDepartment of Chemistry and Biochemistry, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Sohan R JankuruDepartment of Chemistry and Biochemistry, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Susana PortilloDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0002-5210-0797
Cameron C EllisDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0001-7107-6262
Colin D KnightDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0002-2017-0782
Julio Alonso-PadillaBarcelona Institute for Global Health (ISGlobal), 08003 Barcelona, Spain.ORCID 0000-0003-4466-7969
Luis IzquierdoBarcelona Institute for Global Health (ISGlobal), 08003 Barcelona, Spain.ORCID 0000-0002-3704-9874
Maria-Jesus PinazoBarcelona Institute for Global Health (ISGlobal), 08003 Barcelona, Spain.ORCID 0000-0002-4237-1075
Joaquim GasconBarcelona Institute for Global Health (ISGlobal), 08003 Barcelona, Spain.ORCID 0000-0002-5045-1585
Veronica SuarezDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Douglas M WattsDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Iliana R MaloCentro Regional de Investigación en Salud Pública, Instituto Nacional de Salud Pública, Tapachula 30700, Chiapas, Mexico.
Janine M RamseyCentro Regional de Investigación en Salud Pública, Instituto Nacional de Salud Pública, Tapachula 30700, Chiapas, Mexico.ORCID 0000-0002-5950-0830
Belkisyolé Alarcón De NoyaSección de Inmunología, Instituto de Medicina Tropical, Universidad Central de Venezuela, Caracas 1041, Venezuela.
Oscar NoyaSeccion de Biohelmintiasis, Instituto de Medicina Tropical, Universidad Central de Venezuela, Caracas 1041, Venezuela.
Igor C AlmeidaDepartment of Biological Sciences, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.
Katja MichaelDepartment of Chemistry and Biochemistry, Border Biochemical Research Center, The University of Texas at El Paso, El Paso, TX 79968, USA.ORCID 0000-0001-6754-3702
The University of Texas at El Paso · USInstituto de Salud Carlos III · ESCentral University of Venezuela · VEInstituto Nacional de Salud Pública · MX

Funding

TCCG12MD007592 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI KIRKEN, ROBERT A. · 2012 to 2018
$19.4M
RISE Scholars Program at UTEPR25GM069621 · NIGMS · UNIVERSITY OF TEXAS EL PASO · PI AGUILERA, RENATO J · 2004 to 2021
$11.2M
New chemotherapy regimens and biomarkers for Chagas diseaseU01AI129783 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI ALMEIDA, IGOR C, GASCON, JOAQUIM · 2018 to 2024
$7.7M
Synthesis of immunogenic glycolipopeptides for the development of vaccines for ChR21AI079618 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI MICHAEL, KATJA · 2009 to 2010
$373k
National Institute of Allergy and Infectious Diseases R21AI079618National Institute of Allergy and Infectious Diseases U01AI129783National Institute of Health R25GM069621-11NIAID NIH HHS R21 AI079618NIAID NIH HHS U01 AI129783NIGMS NIH HHS R25 GM069621NIH HHS 2G12MD007592NIMHD NIH HHS G12 MD007592
6 · The paper itself

Abstract

Chagas disease (CD) is caused by the parasite

Indexed as

Chagas DiseaseTrypanosoma cruziBiomarkersHumansMucinsTrisaccharidesBiomarkersMucinsTrisaccharidesanti-α-Gal antibodiesbiomarkerChagas diseasechemotherapyoligosaccharide synthesisTrypanosoma cruziα-Gal-containing neoglycoprotein

Identifiers

PMID36080480
PMCPMC9457857
OpenAlexW4295083387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.