Evidence map›Paper›PMID 36080416›Full record

ReviewMolecules (Basel, Switzerland)2022

Virtual Screening in the Identification of Sirtuins' Activity Modulators.

Elena Abbotto, Naomi Scarano, Francesco Piacente, Enrico Millo, Elena Cichero, Santina Bruzzone

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Interplay Between the Circadian Clock and Sirtuins.International journal of molecular sciences · 2024
    Review
  3. Article
  4. Review
  5. Synthesis andFrontiers in chemistry · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Elena AbbottoDepartment of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0001-7161-6353
Naomi ScaranoDepartment of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.ORCID 0000-0002-5121-715X
Francesco PiacenteDepartment of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0001-5470-5987
Enrico MilloDepartment of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0002-4019-0051
Elena CicheroDepartment of Pharmacy, Section of Medicinal Chemistry, School of Medical and Pharmaceutical Sciences, University of Genoa, Viale Benedetto XV, 3, 16132 Genoa, Italy.
Santina BruzzoneDepartment of Experimental Medicine, Section of Biochemistry, University of Genoa, Viale Benedetto XV 1, 16132 Genoa, Italy.ORCID 0000-0003-2034-3716

Funding

European Commission Horizon 2020 Marie Skłodowska-Curie grant No 671881 (INTEGRATA)Ministry of Education, Universities and Research PRIN 2017Z5LR5Z_003
6 · The paper itself

Abstract

Sirtuins are NAD

Indexed as

Diabetes Mellitus, Type 2NeoplasmsNeurodegenerative DiseasesSirtuinsHistonesHumansHistonesSirtuinsactivatorscancerdockinginhibitorsneurodegenerative diseaserational designsirtuinstype 2 diabetesvirtual screening

Identifiers

PMID36080416
PMCPMC9457788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.