Evidence map›Paper›PMID 36080354›Full record

ArticleMolecules (Basel, Switzerland)2022

A Comparative Loading and Release Study of Vancomycin from a Green Mesoporous Silica.

Georgiana Dolete, Bogdan Purcăreanu, Dan Eduard Mihaiescu, Denisa Ficai, Ovidiu-Cristian Oprea, Alexandra Cătălina Bîrcă, Cristina Chircov, Bogdan Ștefan Vasile, Gabriel Vasilievici, Anton Ficai and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Arginine-loaded silica nanoparticles inhibit E. faecalis in root canals.Journal of materials science. Materials in medicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Georgiana DoleteDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0001-9924-1987
Bogdan PurcăreanuBIOTEHNOS SA, Gorunului Street 3-5, 075100 Otopeni, Romania.ORCID 0000-0002-9075-9429
Dan Eduard MihaiescuDepartment of Organic Chemistry "Costin Nenițescu", Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0001-9873-3912
Denisa FicaiNational Center for Micro and Nanomaterials, University POLITEHNICA of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.ORCID 0000-0003-1243-6904
Ovidiu-Cristian OpreaNational Center for Micro and Nanomaterials, University POLITEHNICA of Bucharest, Splaiul Independentei 313, 060042 Bucharest, Romania.ORCID 0000-0002-8145-1094
Alexandra Cătălina BîrcăDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.
Cristina ChircovDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0002-8695-6884
Bogdan Ștefan VasileDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0002-2267-6453
Gabriel VasilieviciNational Institute for Research & Development in Chemistry and Petrochemistry-ICECHIM, Splaiul Independentei 202, 060021 Bucharest, Romania.ORCID 0000-0002-0217-929X
Anton FicaiDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0002-1777-0525
Ecaterina AndronescuDepartment of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Chemical Engineering and Biotechnologies, University POLITEHNICA of Bucharest, Gh. Polizu 1-7, 011061 Bucharest, Romania.ORCID 0000-0002-2226-5849
Universitatea Națională de Știință și Tehnologie Politehnica București · ROAcademia Oamenilor de Știință din România · RONational Institute for Research and Development in Informatics - ICI Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its first use as a drug delivery system, mesoporous silica has proven to be a surprisingly efficient vehicle due to its porous structure. Unfortunately, most synthesis methods are based on using large amounts of surfactants, which are then removed by solvent extraction or heat treatment, leading to an undesired environmental impact because of the generated by-products. Hence, in the present study, we followed the synthesis of a silica material with a wormhole-like pore arrangement, using two FDA-approved substances as templates, namely Tween-20 and starch. As far as we know, it is the first study using the Tween-20/starch combo as a template for mesoporous silica synthesis. Furthermore, we investigated whether the obtained material using this novel synthesis had any potential in using it as a DDS. The material was further analyzed by XRD, TEM, FT-IR, N

Indexed as

Silicon DioxideVancomycinAdsorptionDrug CarriersPolysorbatesPorositySolubilitySolventsSpectroscopy, Fourier Transform InfraredStarchDrug CarriersPolysorbatesSilicon DioxideSolventsStarchVancomycindrug deliverymesoporous silicaphysical mixingsolvent evaporationvacuum-assisted loadingwormhole porosity

Identifiers

PMID36080354
PMCPMC9458150
OpenAlexW4293715074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.