Evidence map›Paper›PMID 36080325›Full record

ArticleMolecules (Basel, Switzerland)2022

2-(Nitroaryl)-5-Substituted-1,3,4-Thiadiazole Derivatives with Antiprotozoal Activities: In Vitro and In Vivo Study.

Alireza Mousavi, Parham Foroumadi, Zahra Emamgholipour, Pascal Mäser, Marcel Kaiser, Alireza Foroumadi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alireza MousaviDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran.
Parham ForoumadiDepartment of Medicinal Chemistry, School of Pharmacy, International Campus, Tehran University of Medical Sciences, Tehran 1417614411, Iran.
Zahra EmamgholipourDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran.
Pascal MäserSwiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland.ORCID 0000-0003-3122-1941
Marcel KaiserSwiss Tropical and Public Health Institute, 4123 Allschwil, Switzerland.ORCID 0000-0003-1785-7302
Alireza ForoumadiDepartment of Medicinal Chemistry, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran 1417614411, Iran.

Funding

Drugs for Neglected Diseases Initiative, Geneva, Switzerland xxNational Institute for Medical Research Development (NIMAD), Tehran, Iran 943604
6 · The paper itself

Abstract

Nitro-containing compounds are a well-known class of anti-infective agents, especially in the field of anti-parasitic drug discovery. HAT or sleeping sickness is a neglected tropical disease caused by a protozoan parasite,

Indexed as

Antiprotozoal AgentsChagas DiseaseTrypanocidal AgentsTrypanosoma brucei bruceiTrypanosomiasis, AfricanAnimalsMiceNeglected DiseasesNitro CompoundsThiadiazolesTrypanosoma brucei rhodesiense1,3,4-thiadiazoleAntiprotozoal AgentsNitro CompoundsThiadiazolesTrypanocidal Agents1,3,4-thiadiazolenitroimidazolesleeping sicknessTrypanosoma brucei

Identifiers

PMID36080325
PMCPMC9457997

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.