Evidence map›Paper›PMID 36080195›Full record

ArticleMolecules (Basel, Switzerland)2022

Biological Effects of EGCG@MOF Zn(BTC)

Song Li, Jing Yan, Qiangqiang Zhu, Xinxiang Liu, Senlin Li, Shenhou Wang, Xuanjun Wang, Jun Sheng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Song LiCollege of Science, Yunnan Agricultural University, Kunming 650201, China.
Jing YanKey Laborotory of Puer Tea Sciencs, Ministry of Education(YNAU), Yunnan Agricultural University, Kunming 650201, China.
Qiangqiang ZhuKey Laborotory of Puer Tea Sciencs, Ministry of Education(YNAU), Yunnan Agricultural University, Kunming 650201, China.
Xinxiang LiuKey Laborotory of Puer Tea Sciencs, Ministry of Education(YNAU), Yunnan Agricultural University, Kunming 650201, China.
Senlin LiCollege of Science, Yunnan Agricultural University, Kunming 650201, China.
Shenhou WangCollege of Science, Yunnan Agricultural University, Kunming 650201, China.
Xuanjun WangCollege of Science, Yunnan Agricultural University, Kunming 650201, China.
Jun ShengKey Laborotory of Puer Tea Sciencs, Ministry of Education(YNAU), Yunnan Agricultural University, Kunming 650201, China.
Yunnan Agricultural University · CN

Funding

Applied Basic Research Program of Yunnan Province 2019FB024National Natural Science Foundation of China 21965038
6 · The paper itself

Abstract

Tea contains high levels of the compound epigallocatechin gallate (EGCG). It is considered an important functional component in tea and has anti-cancer, antioxidant, and anti-inflammatory effects. The eight phenolic hydroxyl groups in EGCG's chemical structure are the basis for EGCG's multiple biological effects. At the same time, it also leads to poor chemical stability, rendering EGCG prone to oxidation and isomerization reactions that change its original structure and biological activity. Learning how to maintain the activity of EGCG has become an important goal in understanding the biological activity of EGCG and the research and development of tea-related products. Metal-organic frameworks (MOFs) are porous materials with a three-dimensional network structure that are composed of inorganic metals or metal clusters together with organic complexes. MOFs exploit the porous nature of the material itself. When a drug is an appropriate size, it can be wrapped into the pores by physical or chemical methods; this allows the drug to be released slowly, and MOFs can also reduce drug toxicity. In this study, we used MOF Zn(BTC)

Indexed as

CatechinDiabetes MellitusAnimalsMiceTeaWound HealingZincCatechinepigallocatechin gallateTeaZincdiabetesEGCGMOFwound healing

Identifiers

PMID36080195
PMCPMC9458255
OpenAlexW4293217932

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.