Evidence map›Paper›PMID 36080103›Full record

ReviewNanomaterials (Basel, Switzerland)2022

Current Research on Zinc Oxide Nanoparticles: Synthesis, Characterization, and Biomedical Applications.

Ashok Kumar Mandal, Saurav Katuwal, Felix Tettey, Aakash Gupta, Salyan Bhattarai, Shankar Jaisi, Devi Prasad Bhandari, Ajay Kumar Shah, Narayan Bhattarai, Niranjan Parajuli

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Zinc oxide-bacteriophage synergistic combination for dual-mode antibacterial activity against multidrug-resistant Escherichia coli.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Phytofabrication of Zinc Oxide Nanoparticles UsingBioinorganic chemistry and applications · 2026
    Article
  15. Green-synthesized ZnO nanoparticles fromFrontiers in plant science · 2026
    Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ashok Kumar MandalNatural Product Research Laboratory, Thapathali, Kathmandu 44600, Nepal.ORCID 0000-0003-1210-4264
Saurav KatuwalCentral Department of Chemistry, Tribhuvan University, Kirtipur 44618, Nepal.ORCID 0000-0003-0570-865X
Felix TetteyDepartment of Chemical, Biological, and Bioengineering, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0002-2101-0131
Aakash GuptaDepartment of Chemistry and Biochemistry, University of Massachusetts Dartmouth, North Dartmouth, MA 02747, USA.ORCID 0000-0003-4799-0593
Salyan BhattaraiParaza Pharma, Inc., 2525 Avenue Marie-Curie, Montreal, QC H4S 2E1, Canada.ORCID 0000-0002-6553-0286
Shankar JaisiCentral Department of Chemistry, Tribhuvan University, Kirtipur 44618, Nepal.ORCID 0000-0002-7476-915X
Devi Prasad BhandariNatural Product Research Laboratory, Thapathali, Kathmandu 44600, Nepal.ORCID 0000-0002-1104-6173
Ajay Kumar ShahFaculty of Health Sciences, School of Health and Allied Sciences, Pokhara University, Lekhnath 33700, Nepal.ORCID 0000-0003-4867-6483
Narayan BhattaraiDepartment of Chemical, Biological, and Bioengineering, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0002-0583-7913
Niranjan ParajuliCentral Department of Chemistry, Tribhuvan University, Kirtipur 44618, Nepal.ORCID 0000-0002-9233-6489

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc oxide nanoparticles (ZnO-NPs) have piqued the curiosity of researchers all over the world due to their extensive biological activity. They are less toxic and biodegradable with the capacity to greatly boost pharmacophore bioactivity. ZnO-NPs are the most extensively used metal oxide nanoparticles in electronic and optoelectronics because of their distinctive optical and chemical properties which can be readily modified by altering the morphology and the wide bandgap. The biosynthesis of nanoparticles using extracts of therapeutic plants, fungi, bacteria, algae, etc., improves their stability and biocompatibility in many biological settings, and its biofabrication alters its physiochemical behavior, contributing to biological potency. As such, ZnO-NPs can be used as an effective nanocarrier for conventional drugs due to their cost-effectiveness and benefits of being biodegradable and biocompatible. This article covers a comprehensive review of different synthesis approaches of ZnO-NPs including physical, chemical, biochemical, and green synthesis techniques, and also emphasizes their biopotency through antibacterial, antifungal, anticancer, anti-inflammatory, antidiabetic, antioxidant, antiviral, wound healing, and cardioprotective activity. Green synthesis from plants, bacteria, and fungus is given special attention, with a particular emphasis on extraction techniques, precursors used for the synthesis and reaction conditions, characterization techniques, and surface morphology of the particles.

Indexed as

biological activitiesgreen synthesiszinc oxide nanoparticles

Identifiers

PMID36080103
PMCPMC9459703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.