Evidence map›Paper›PMID 36079990›Full record

ArticleNanomaterials (Basel, Switzerland)2022

Box-Behnken Design: Optimization of Proanthocyanidin-Loaded Transferosomes as an Effective Therapeutic Approach for Osteoarthritis.

Neelakandan Tamilarasan, Begum M Yasmin, Posina Anitha, Hani Umme, Wan Hee Cheng, Sellapan Mohan, Sundarapandian Ramkanth, Ashok Kumar Janakiraman

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Nanophytosomal Gel ofPharmaceuticals (Basel, Switzerland) · 2024
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  6. Dermal Delivery ofRecent advances in drug delivery and formulation · 2024
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Neelakandan TamilarasanDepartment of Pharmaceutics, Karpagam College of Pharmacy, Coimbatore 641032, TN, India.
Begum M YasminDepartment of Pharmaceutics, King Khalid University, Abha 62529, Saudi Arabia.ORCID 0000-0002-1871-8585
Posina AnithaDepartment of Pharmaceutics, Annamacharya College of Pharmacy, Rajampet 516126, AP, India.ORCID 0000-0003-0061-2085
Hani UmmeDepartment of Pharmaceutics, King Khalid University, Abha 62529, Saudi Arabia.
Wan Hee ChengFaculty of Health and Life Sciences, INTI International University, Nilai 71800, Negeri Sembilan, Malaysia.ORCID 0000-0002-2311-2377
Sellapan MohanDepartment of Pharmaceutics, Karpagam College of Pharmacy, Coimbatore 641032, TN, India.ORCID 0000-0002-4026-9405
Sundarapandian RamkanthDepartment of Pharmaceutics, Karpagam College of Pharmacy, Coimbatore 641032, TN, India.ORCID 0000-0002-2987-1526
Ashok Kumar JanakiramanFaculty of Pharmaceutical Sciences, UCSI University, Cheras, Kuala Lumpur 56000, Malaysia.ORCID 0000-0002-9670-8323
Karpagam Academy of Higher Education · INKing Khalid University · SAINTI International University · MYUCSI University · MY

Funding

Deanship of Scientific Research RGP.2/31/43
6 · The paper itself

Abstract

Transferosomes are one of the vesicular carriers that have received extensive research and attention recently because of their capacity to get beyond the barriers posed by the stratum corneum to penetration. The intent of the current study is to optimize and evaluate proanthocyanidin (PAC) containing transferosomal transdermal gels. PAC-containing transferosomes were prepared using the film hydration method and then loaded into a 4% methylcellulose gel. A 2

Indexed as

Box–Behnkenentrapment efficiencyproanthocyanidintransferosomes

Identifiers

PMID36079990
PMCPMC9457895
OpenAlexW4293771737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.