Regulation of Antimicrobial Effect of Hemicyanine-Based Photosensitizer via Supramolecular Assembly.

Huanxiang Yuan, Shaochuan Jia, Zelin Li, Jian Liu, Xiaoyu Wang, Ruilian Qi

Abstract read

In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Supramolecular Switch for the Regulation of Antibacterial Efficacy of Near-Infrared Photosensitizer.Molecules (Basel, Switzerland) · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Huanxiang YuanDepartment of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.

Shaochuan JiaDepartment of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.

Zelin LiDepartment of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.

Jian LiuInstitute of Chemistry, Chinese Academy of Sciences, Beijing 100090, China.ORCID 0000-0002-9853-3619

Xiaoyu WangSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing 100083, China.ORCID 0000-0002-2139-3152

Ruilian QiDepartment of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, China.

Funding

Beijing Municipal Education Commission KM202210011002Fundamental Research Funds for the Central Universities FRF-IDRY-20-026

6 · The paper itself

Abstract

An intelligent "antimicrobial switch" has been constructed to reduce prolonged exposure of pathogenic bacteria to antibiotics, which could reversibly "turn off" or "turn on" the antimicrobial activity of hemicyanines through self-assembly or dis-assembly of cucurbit[7]uril (CB[7]). This assembly effectively inhibited the production of ROS under light, shielding the active site of hemicyanines and achieving on-demand antimicrobial ability. Moreover, CB[7] differentially inhibits ROS of molecules with different alkyl chain lengths, which provided reference for the subsequent design of materials with antimicrobial activity regulation, and could effectively delay or even prevent the development of pathogens resistance.

Indexed as

hemicyaninephotodynamic therapyphotosensitizersupramolecular assembly

Identifiers

PMID36079943

DOI10.3390/nano12172905

PMCPMC9457667

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.