Evidence map›Paper›PMID 36079903›Full record

ArticleNutrients2022

Neonatal Morbidities and Feeding Tolerance Outcomes in Very Preterm Infants, before and after Introduction of Probiotic Supplementation.

Ayoub Mitha, Sofia Söderquist Kruth, Sara Bjurman, Alexander Rakow, Stefan Johansson

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Early supplementation with live combinedFrontiers in cellular and infection microbiology · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Ayoub MithaDepartment of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0001-7203-3205
Sofia Söderquist KruthWomen's Health and Allied Health Professional Theme, Karolinska University Hospital, Solna, 17176 Stockholm, Sweden.
Sara BjurmanSachs Children and Youth Hospital, Södersjukhuset, 11883 Stockholm, Sweden.
Alexander RakowDepartment of Women's and Children's Health, Karolinska Institutet, 17177 Stockholm, Sweden.
Stefan JohanssonDepartment of Medicine Solna, Clinical Epidemiology Division, Karolinska Institutet, 17177 Stockholm, Sweden.ORCID 0000-0001-8832-6918
Karolinska University Hospital · SEKarolinska Institutet · SEStockholm South General Hospital · SEUniversité de Lille · FR

Funding

Föreningen Mjölkdroppen xxKarolinska Institute 2020-01928Stiftelsen Allmänna BBs Minnesfond xx
6 · The paper itself

Abstract

While probiotics are reported to reduce the risks of neonatal morbidities, less is known about probiotics and feeding tolerance. With this retrospective cohort study, we investigate whether introduction of probiotic supplementation as the standard of care was associated with fewer neonatal morbidities and improved feeding tolerance in very preterm infants. Using the Swedish Neonatal Quality Register, 345 live-born very preterm infants (28-31 weeks' gestation), from January 2019-August 2021, in NICUs in Stockholm, Sweden, either received probiotic supplementation (

Indexed as

Enterocolitis, NecrotizingInfant, Premature, DiseasesProbioticsAnti-Bacterial AgentsFemaleFetal Growth RetardationHumansInfantInfant, NewbornInfant, PrematureMorbidityRetrospective StudiesAnti-Bacterial Agentsantibioticfeeding tolerancefull enteral feedingnecrotising enterocolitisneonatal morbiditiesprobiotic supplementationvery preterm infants

Identifiers

PMID36079903
PMCPMC9460632
OpenAlexW4295080335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.