Evidence map›Paper›PMID 36079886›Full record

SynthesisNutrients2022

The Potential of Pectins to Modulate the Human Gut Microbiota Evaluated by In Vitro Fermentation: A Systematic Review.

Nélida Pascale, Fangjie Gu, Nadja Larsen, Lene Jespersen, Frederique Respondek

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 100 citations in OpenAlex.

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  12. Improving Growth Dynamics ofInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nélida PascaleCP Kelco, Cumberland Center II, 3100 Cumberland Boulevard, Suite 600, Atlanta, GA 30339, USA.
Fangjie GuCP Kelco, Cumberland Center II, 3100 Cumberland Boulevard, Suite 600, Atlanta, GA 30339, USA.
Nadja LarsenDepartment of Food Science, University of Copenhagen, Rolighedsvej 26, 1958 Frederiksberg, Denmark.
Lene JespersenDepartment of Food Science, University of Copenhagen, Rolighedsvej 26, 1958 Frederiksberg, Denmark.ORCID 0000-0002-2555-5948
Frederique RespondekCP Kelco, 123 rue Jules Guesde, 92300 Levallois-Perret, France.
University of Copenhagen · DK

Funding

CP Kelco not applicable
6 · The paper itself

Abstract

Pectin is a dietary fiber, and its health effects have been described extensively. Although there are limited clinical studies, there is a growing body of evidence from in vitro studies investigating the effect of pectin on human gut microbiota. This comprehensive review summarizes the findings of gut microbiota modulation in vitro as assessed by 16S rRNA gene-based technologies and elucidates the potential structure-activity relationships. Generally, pectic substrates are slowly but completely fermented, with a greater production of acetate compared with other fibers. Their fermentation, either directly or by cross-feeding interactions, results in the increased abundances of gut bacterial communities such as the family of

Indexed as

Gastrointestinal MicrobiomeBacteriaEubacterialesFecesFermentationHumansPectinsPrebioticsRNA, Ribosomal, 16SPectinsPrebioticsRNA, Ribosomal, 16Sdietary fibergut healthhumanmicrobiotapectinprebiotic

Identifiers

PMID36079886
PMCPMC9460662
OpenAlexW4295083672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.