ReviewNutrients2022
Iodine and Iodine Deficiency: A Comprehensive Review of a Re-Emerging Issue.
Review in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
101 citing papers in PubMed, 3 syntheses or guidelines pooled it, 195 citations in OpenAlex.
- Effects of different iodine supplementation strategies on thyroid function in iodine-deficient pregnant women: a meta-analysis.Frontiers in public health · 2026Pooled it
- Prevalence and Determinants of Stunting-Anemia and Wasting-Anemia Comorbidities and Micronutrient Deficiencies in Children Under 5 in the Least-Developed Countries: A Systematic Review and Meta-analysis.Nutrition reviews · 2025Pooled it
- Prevalence of iodine deficiency and associated factors among school-age children in Ethiopia: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- Association between serum iodine and thyroid function in Malagasy adults: a cross-sectional study in a tertiary-level hospital in Antananarivo, Madagascar.The Libyan journal of medicine · 2026Article
- Micronutrient risk with GLP-1 receptor and dual incretin agonists in obesity: Mechanistic pathways, clinical signals, and a monitoring framework.Obesity pillars · 2026Review
- The role of nutrition on thyroid health and disease: myths and facts.Journal of endocrinological investigation · 2026Review
- [Review and comment "Guidance for salt fortification with iodine: a renewed commitment to achieve optimal iodine nutrition"].Problemy endokrinologii · 2026Review
- Effects of per- and polyfluoroalkyl substances on maternal thyroid function: a stratified analysis by maternal iodine status and thyroid autoantibody status.BMC pregnancy and childbirth · 2026Article
- Establishment of Thyroid Volume Reference Curves for Children in Xinjiang: An Exploration of Goiter Diagnosis and the Role of Iodine Nutrition.Biological trace element research · 2026Article
- Nationwide survey on iodine nutritional status and thyroid function in Japanese adults.Endocrine journal · 2026Observational
- Iodine Fortification of a Fermented Dairy Product: Development and Quality Assessment.Foods (Basel, Switzerland) · 2026Article
- The effectiveness of education-based interventions on iodine knowledge, attitude, behaviour, and status: a systematic review protocol.Systematic reviews · 2026Article
- First population-based national eHealth system study on the prevalence of nonmalignant thyroid disorders in North Macedonia: A cross-sectional analysis.The Journal of international medical research · 2026Article
- Article
- Seaweed bioactives: A comprehensive review of their nutritional, medicinal, and functional roles.iScience · 2026Review
- Sample Size and Optimal Timing for Urine Collection Based on Diurnal Variability of Urinary Iodine/Creatinine Ratio in Pregnant Women.Biological trace element research · 2026Observational
- Article
- Enhancing iodine health awareness among adolescents: a study protocol for a multi-country intervention study in educational settings across the UK, Slovenia, Cyprus, Bangladesh, Germany and Pakistan.BMC public health · 2026Article
- Empirical comparison of iodine excretion estimated from spot urine samples with measured 24-hour urinary iodine excretion in healthy adults.Journal of the Chinese Medical Association : JCMA · 2026Article
- Iodine deficiency and excess in children and related factors in Alborz Province: a cross-sectional study.BMC nutrition · 2026Article
41 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Iodine is a mineral nutrient essential for the regulation of a variety of key physiological functions including metabolism and brain development and function in children and adults. As such, iodine intake and status within populations is an area of concern and research focus. This paper will review recently published studies that focus on the re-emerging issue of iodine deficiency as a global concern and declining intake among populations in developed countries. Historically, the implementation of salt-iodization programs worldwide has reduced the incidence of iodine deficiency, but 30% of the world's population is still at risk. Iodine nutrition is a growing issue within industrialized countries including the U.S. as a result of declining iodine intake, in part due to changing dietary patterns and food manufacturing practices. Few countries mandate universal salt iodization policies, and differing agriculture and industry practices and regulations among countries have resulted in inconsistencies in supplementation practices. In the U.S., in spite of salt-iodization policies, mild-to-moderate iodine deficiency is common and appears to be increasing. European countries with the highest incidence of deficiency lack iodization programs. Monitoring the iodine status of at-risk populations and, when appropriate, public health initiatives, appear to be warranted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.