Evidence map›Paper›PMID 36079655›Full record

ArticlePlants (Basel, Switzerland)2022

Synthesis and Activity of 2-Acyl-cyclohexane-1,3-dione Congeners Derived from

Joey K Ooka, Mauro V Correia, Marcus T Scotti, Harold H Fokoue, Lydia F Yamaguchi, Massuo J Kato, Franck E Dayan, Daniel K Owens

Open access · goldAbstract read
In one paragraph

Article in Plants (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Joey K OokaDepartment of Molecular Biosciences and Bioengineering, University of Hawaii-Manoa, Honolulu, HI 96822, USA.ORCID 0000-0002-1730-2924
Mauro V CorreiaInstitute of Chemistry, University of Brasilia, Brasilia 70910-900, DF, Brazil.ORCID 0000-0003-3880-180X
Marcus T ScottiDepartment of Chemistry, Federal University of Paraiba, Brasilia 58051-900, PB, Brazil.
Harold H FokoueLaboratório de Avaliação e Síntese de Substâncias Bioativas (LASSBio®), Instituto de Ciências Biomédicas, Centro das Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-901, RJ, Brazil.ORCID 0000-0001-7823-127X
Lydia F YamaguchiInstitute of Chemistry, University of São Paulo, São Paulo 03001-000, SP, Brazil.ORCID 0000-0003-2305-8208
Massuo J KatoInstitute of Chemistry, University of São Paulo, São Paulo 03001-000, SP, Brazil.ORCID 0000-0002-3315-2129
Franck E DayanAgricultural Biology, Colorado State University, Fort Collins, CO 80526, USA.ORCID 0000-0001-6964-2499
Daniel K OwensDepartment of Molecular Biosciences and Bioengineering, University of Hawaii-Manoa, Honolulu, HI 96822, USA.
Universidade de São Paulo · BRUniversity of Hawaiʻi at Mānoa · USColorado State University · USUniversidade de Brasília · BRUniversidade Federal da Paraíba · BRUniversidade Federal do Rio de Janeiro · BR

Funding

FAPESP 50316-7PRP-USP NAP-PNUSDA National Institute of Food and Agriculture COL00785USDA NIFA HAW-05033-H
6 · The paper itself

Abstract

Plastoquinone is a key electron carrier in photosynthesis and an essential cofactor for the biosynthesis of carotenoids. p-Hydroxyphenylpyruvate dioxygenase (HPPD) is a vital enzymatic step in plastoquinone biosynthesis that is the target of triketone herbicides, such as those derived from the pharmacophore backbone of the natural product leptospermone. In this work, the inhibitory activity of a series of 2-acyl-cyclohexane-1,3-diones congeners derived from

Indexed as

essentialherbicide mode of actionnatural productsp-hydroxyphenylpyruvate dioxygenasephytotoxinsquantitative structure-activity relationshipssynthesistriketones

Identifiers

PMID36079655
PMCPMC9459959
OpenAlexW4294251814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.