Evidence map›Paper›PMID 36079344›Full record

ArticleMaterials (Basel, Switzerland)2022

Photothermal-Controlled Release of IL-4 in IL-4/PDA-Immobilized Black Titanium Dioxide (TiO

Bo Chen, Yu Liang, Yunjia Song, Yunkai Liang, Jian Jiao, Hong Bai, Ying Li

Open access · goldAbstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Engineering the Immune Response to Biomaterials.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. How TiOInternational journal of nanomedicine · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Bo ChenSchool of Dentistry, Tianjin Medical University, Tianjin 300070, China.
Yu LiangSchool of Dentistry, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0002-9991-9898
Yunjia SongSchool of Dentistry, Tianjin Medical University, Tianjin 300070, China.
Yunkai LiangSchool of Dentistry, Tianjin Medical University, Tianjin 300070, China.
Jian JiaoSchool of Dentistry, Tianjin Medical University, Tianjin 300070, China.ORCID 0000-0001-6002-7297
Hong BaiTianjin Key Laboratory of Cellular and Molecular Immunology and Key Laboratory of the Educational Ministry of China, Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin 300070, China.
Ying LiSchool of Dentistry, Tianjin Medical University, Tianjin 300070, China.
Tianjin Medical University · CN

Funding

National Natural Science Foundation of China 82171008, 81870809Scientific Research Project of Tianjin Education Commission 2020KJ183, 2021YJSS160Tianjin Health Science and Technology Project ZD20021, TJWJ2021QN041, TJWJ2021QN042, KJ20010
6 · The paper itself

Abstract

Host immune response has gradually been accepted as a critical factor in achieving successful implant osseointegration. The aim of this study is to create a favorable immune microenvironment by the dominant release of IL-4 during the initial few days after implant insertion to mitigate early inflammatory reactions and facilitate osseointegration. Herein, the B-TNT/PDA/IL-4 substrate was established by immobilizing an interleukin-4 (IL-4)/polydopamine (PDA) coating on a black TiO

Indexed as

controlled releaseIL-4near-infrared laserosseointegrationPDAphotothermalTiO2 nanotubestitanium

Identifiers

PMID36079344
PMCPMC9457063
OpenAlexW4293730544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.