ArticleJournal of clinical medicine2022
Health-Related Quality of Life (HRQoL) and the Effect on Outcome in Patients Presenting with Coronary Artery Disease and Treated with Percutaneous Coronary Intervention (PCI): Differences Noted by Sex and Age.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The Effects of Interventions on Health-Related Quality of Life of People Living With Cardiovascular Disease: A Systematic Review.Journal of clinical nursing · 2025Pooled it
- Impact of complete versus culprit-only revascularization on major adverse cardiovascular event in diverse subpopulations.Future cardiology · 2024Pooled it
- High-intensity interval training versus moderate-intensity continuous training on exercise capacity and health-related quality of life in patients with coronary artery disease: An updated systematic review and meta-analysis.Brazilian journal of physical therapyPooled it
- The Effect of Age on Improvement in Health-Related Quality of Life After Percutaneous Coronary Intervention.Clinical cardiology · 2026Trial
- Health-related quality of life after acute myocardial infarction and one-year clinical outcomes: A prospective cohort study.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Lifestyle Habits and Comorbidities as Determinants of Quality of Life in Coronary Artery Disease: A Single-Center Prospective Study.Journal of clinical medicine · 2026Article
- Article
- Healthy Lifestyle and Its Relationship with Health-Related Quality of Life in Cardiovascular Patients: A Cross-Sectional Study.Journal of lifestyle medicine · 2025Article
- Health-Related QoL of Hypertensive Patients in Bulgaria-Population-Based, Regional Pilot Study.Medicina (Kaunas, Lithuania) · 2025Observational
- Impact of Percutaneous Coronary Interventions (PCIs) on Health Outcomes from a Jordanian Patient's Perspective.Healthcare (Basel, Switzerland) · 2025Article
- Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study.JMIR human factors · 2025Article
- Long-Term Follow-Up of HRQoL up to Six Years after Outpatient Phase-II Cardiac Rehabilitation.Healthcare (Basel, Switzerland) · 2024Article
- Special Issue "Clinical Frontiers in Percutaneous Coronary Intervention".Journal of clinical medicine · 2023Article
- Comprehensive Geriatric Care in Older Hospitalized Patients with Depressive Symptoms.Geriatrics (Basel, Switzerland) · 2023Article
- Factors associated with health-related quality of life in patients undergoing percutaneous coronary intervention: Thai PCI registry.Frontiers in cardiovascular medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and aim: poor quality of life (QoL) has been identified as an independent risk factor for mortality and major cardiac events (MACE) in patients with cardiovascular disease (CVD). The aim of this study was to assess health-related quality of life (HRQoL) at baseline and its association with outcome in patients with coronary artery disease presenting for percutaneous coronary intervention (PCI). The outcome was measured by mortality and MACE at 1-year, and whether there was any difference for sex and different age groups. Methods and results: all patients prospectively enrolled into the GenesisCare Outcome Registry (GCOR) over a 11-year period were included in the study. The EQ-5D-5L and VAS patient survey were used for assessment of baseline HRQoL. Of the 15,198 patients, only 6591 (43.4%) completed the self-assessment. Women had significantly more impairment of all five dimensions of the EQ-5D-5L survey, and their self-reported QoL was significantly lower than men (68.3 in women vs. 71.9 in men, p < 0.001). Poor QoL was strongly associated with increased mortality (HR 2.85; 95% CI 1.76 to 4.62, p < 0.001) and MACE (HR 1.40; 95% CI 1.10 to 1.79, p = 0.01). A similar trend was noted for women and men, but did not reach significance in women due to the smaller number of female patients. Conclusion: poor HRQoL is associated with subsequent mortality and MACE in patients undergoing PCI. By not assessing quality of life as a standard of care, an opportunity is lost to identify high-risk patients who may benefit from targeted interventions to improve health outcomes.
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Registered trials
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