ReviewJournal of clinical medicine2022
The Efficacy of Early Interventions for Children with Autism Spectrum Disorders: A Systematic Review and Meta-Analysis.
Review in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 4 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Parent-Mediated Interventions for ASD Under 3 Years: A Systematic Review, Meta Analysis, and Moderator Analyses.Journal of autism and developmental disorders · 2026Pooled it
- The Views of Autistic Adults on Early Autism Interventions: A Mixed-Methods Systematic Literature Review.Autism : the international journal of research and practice · 2026Pooled it
- Analyzing the influence of physical exercise interventions on social skills in children with autism spectrum disorder: insights from meta-analysis.Frontiers in psychology · 2024Pooled it
- Social media interventions for autistic individuals: Systematic review.Frontiers in psychiatry · 2023Pooled it
- Arabic Language Autism Diagnostic Interview (ALADIN): A Validation Study.Journal of autism and developmental disorders · 2026Article
- Childhood post-adoption experiences and the long-term trajectories of deprivation-specific neurodevelopmental problems: a longitudinal study of the English and Romanian adoptee cohort.European child & adolescent psychiatry · 2026Article
- Early Intervention and Social Decision-Making Skills in Children With Autism Spectrum Disorder: Insights from Jordan.Journal of autism and developmental disorders · 2026Article
- The Language Gap: Disparities in Expressive Versus Receptive Language in Young Children With Neurodevelopmental Conditions.Journal of autism and developmental disorders · 2026Article
- Community education program on autism spectrum disorder: a case study of an ecosystem intervention involving family, school, NGO, and community stakeholders.Frontiers in public health · 2026Article
- Transmethylation and Oxidative Biomarkers in Children with Autism Spectrum Disorder: A Cross Sectional Study.Journal of autism and developmental disorders · 2026Article
- Effectiveness and experiences of early intensive behavioral and naturalistic developmental behavior interventions for autism spectrum disorders: a mixed-methods systematic review and meta-analysis.Child and adolescent psychiatry and mental health · 2025Review
- Early Parent-Mediated Training for Social-Communication Skills in Toddlers and Preschoolers With ASD: A Systematic Review and Meta-analysis.Journal of autism and developmental disorders · 2025Article
- Association of maternal endometriosis with autism spectrum disorder in offspring: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Collaborating with an autism community advisory board to develop a family-based, neurodiversity-affirming intervention: PCIT-Autism.Research involvement and engagement · 2025Article
- Efficacy of structured teaching program for rehabilitation of children with autism spectrum disorder: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Review
- Review
- Linking autism risk genes to morphological and pharmaceutical screening by high-content imaging: Future directions and opinion.Psychiatry and clinical neurosciences · 2025Review
- Families' and clinicians' experiences with telehealth assessments for autism: A mixed-methods systematic review.PLOS digital health · 2025Article
- Developmental Disturbances in Animal Models of Autism Spectrum Disorder.Developmental neurobiology · 2025Review
- Randomized Controlled Trial of Developmental Reciprocity Treatment in Young Children with Autism.Journal of autism and developmental disorders · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The superiority of early interventions for children with autism spectrum disorders (ASDs) compared to treatment as usual (TAU) has recently been questioned. This study was aimed to investigate the efficacy of early interventions in improving the cognitive ability, language, and adaptive behavior of pre-school children with ASDs through a systematic review of randomized controlled trials (RCTs). In total, 33 RCTs were included in the meta-analysis using the random effects model. The total sample consisted of 2581 children (age range: 12-132 months). Early interventions led to positive outcomes for cognitive ability (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.