ArticleJournal of clinical medicine2022
Changes in the Urinary Sodium-to-Potassium Ratio Are Associated with Blood Pressure Change in Older Japanese Adults: A 7-Year Longitudinal Study.
Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- A Randomized Clinical Trial of ICT-based Interventions for Sodium and Potassium Regulation in Healthy Adults.American journal of hypertension · 2025Trial
- Are changes in the urinary sodium-to-potassium ratio associated with changes in blood pressure in a healthy population with low urinary sodium-to-potassium ratios? Eight-year follow-up results from the KOBE Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Elevated NaInternational journal of molecular sciences · 2026Article
- Non-use of dentures after tooth loss is associated with elevated sodium/potassium ratios in older adults: a retrospective cohort study.Frontiers in dental medicine · 2025Article
- Spot urinary sodium-to-potassium ratio is associated with blood pressure levels in healthy adolescents: the Wakayama Study.Journal of human hypertension · 2024Article
- Association between sodium-to-potassium ratio in spot urine and hospitalization due to heart failure in high-risk Japanese patients.International journal of cardiology. Heart & vasculature · 2024Article
- Association between spot urinary sodium-to-potassium ratio and blood pressure among Chinese adults aged 18-69 years: the SMASH study.Frontiers in nutrition · 2024Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Studies on the association between sodium-to-potassium (Na/K) ratio changes and blood pressure (BP) changes among older adults are limited. This 7-year longitudinal study examined the association between Na/K ratio changes (evaluated using spot urine tests) and BP changes among older Japanese adults. Data were collected from 432 participants (mean age: 70.3±4.4; range: 65−84 years) in 2012 and 2019. Changes in BP and the Na/K ratio over 7 years were calculated by subtracting baseline values from values noted during a follow-up survey. The median systolic and diastolic BP (SBP) and (DBP) changes after 7 years were 4 (IQR, −7, 14) and −1 (IQR, −9, 5) mmHg, respectively. The median Na/K ratio was changed during the follow-up period by −0.2 (IQR, −1.3, 0.7). A generalized linear model indicated that Na/K ratio changes were positively associated with SBP (B = 2.03, p < 0.001) and DBP (B = 0.62, p = 0.021) changes. In the non-antihypertensive medication-using group, urinary Na/K ratio changes were associated with SBP and DBP changes (B = 2.39, p = 0.001; B = 0.99, p = 0.033). In the antihypertensive medication user group, urinary Na/K ratio changes were associated with SBP changes (B = 1.62, p = 0.015). We confirmed the association between changes in the Na/K ratio and changes in BP.
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