Evidence map›Paper›PMID 36078930›Full record

ArticleJournal of clinical medicine2022

Cardiac Magnetic Resonance Shows Improved Outcomes in Patients with an ST-Segment Elevation Myocardial Infarction and a High Thrombus Burden Treated with Adjuvant Aspiration Thrombectomy.

Wojciech Zajdel, Tomasz Miszalski-Jamka, Jarosław Zalewski, Jacek Legutko, Krzysztof Żmudka, Elżbieta Paszek

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wojciech ZajdelClinical Department of Interventional Cardiology, The John Paul II Hospital, Pradnicka 80, 31-202 Krakow, Poland.ORCID 0000-0001-7284-2117
Tomasz Miszalski-JamkaDepartment of Radiology and Imaging Diagnostics, The John Paul II Hospital, Pradnicka 80, 31-202 Krakow, Poland.
Jarosław ZalewskiDepartment of Coronary Artery Disease and Heart Failure, Jagiellonian University Medical College, sw. Anny 12, 31-008 Krakow, Poland.ORCID 0000-0002-4374-3694
Jacek LegutkoClinical Department of Interventional Cardiology, The John Paul II Hospital, Pradnicka 80, 31-202 Krakow, Poland.
Krzysztof ŻmudkaClinical Department of Interventional Cardiology, The John Paul II Hospital, Pradnicka 80, 31-202 Krakow, Poland.
Elżbieta PaszekClinical Department of Interventional Cardiology, The John Paul II Hospital, Pradnicka 80, 31-202 Krakow, Poland.ORCID 0000-0002-8389-9407
Jagiellonian University · PLJohn Paul II Hospital · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a discrepancy between epicardial vessel patency and microcirculation perfusion in a third of patients treated with percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). Optimization with aspiration thrombectomy (AT) may reduce distal embolization and microvascular obstruction. The effect of AT in the treatment of STEMI is debatable. The purpose of this study was to use cardiac magnetic resonance (CMR) to determine whether AT influences microvascular obstruction (MVO), infarct size and left ventricular (LV) remodelling in STEMI patients. Sixty STEMI patients with a thrombus-occluded coronary artery were randomized in a 2:1 fashion to receive PCI proceeded by AT (AT + PCI group), or PCI only. MVO, myocardial infarct size and LV remodelling were assessed by CMR during the index hospitalization and 6 months thereafter. The majority of patients had a large thrombus burden (TIMI thrombus grade 5 in over 70% of patients). PCI and AT were effective in all cases. There were no periprocedural strokes. CMR showed that the addition of AT to standard PCI was associated with lesser MVO when indexed to the infarct size and larger infarct size reduction. There were less patients with left ventricle remodelling in the AT + PCI vs. the PCI only group. To conclude, in STEMI patients with a high thrombus burden, AT added to PCI is effective in reducing infarct size, MVO and LV remodelling.

Indexed as

aspiration thrombectomycardiac magnetic resonanceleft ventricular remodellingmicrovascular obstructionST-segment-elevation myocardial infarction

Identifiers

PMID36078930
PMCPMC9456619
OpenAlexW4293217555

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.