Evidence map›Paper›PMID 36078888›Full record

ArticleJournal of clinical medicine2022

Inodilators May Improve the In-Hospital Mortality of Patients with Cardiogenic Shock Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation.

Mijoo Kim, Seok-Woo Seong, Pil Sang Song, Jin-Ok Jeong, Jeong Hoon Yang, Hyeon-Cheol Gwon, Young-Guk Ko, Cheol Woong Yu, Woo Jung Chun, Woo Jin Jang and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02985008 (SMart Angioplasty Research Team), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02985008 unknown statusnot on this map

SMart Angioplasty Research Team: A Multi-center, Open, REtrospective and Prospective Observational Study to Investigate Clinical oUtcomes and Efficacy of Left Ventricular Assist Device for Korean Patients With Cardiogenic Shock : RESCUE

Typeobservational_patient_registrySponsorJeong Hoon YangRan2016 to 2019Enrolled1,000ConditionsShock, Cardiogenic
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Interaction of milrinone with extracorporeal life support.The journal of extra-corporeal technology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mijoo KimDivision of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon 35015, Korea.ORCID 0000-0003-0117-4873
Seok-Woo SeongDivision of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon 35015, Korea.
Pil Sang SongDivision of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon 35015, Korea.ORCID 0000-0001-6427-3911
Jin-Ok JeongDivision of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon 35015, Korea.ORCID 0000-0003-0763-4754
Jeong Hoon YangDivision of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Hyeon-Cheol GwonDivision of Cardiology, Department of Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 06351, Korea.
Young-Guk KoDivision of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.
Cheol Woong YuDivision of Cardiology, Department of Internal Medicine, Korea University Anam Hospital, Seoul 02841, Korea.ORCID 0000-0002-5871-4562
Woo Jung ChunDepartment of Cardiology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea.ORCID 0000-0001-7637-906X
Woo Jin JangDepartment of Cardiology, Ewha Woman's University Seoul Hospital, Ehwa Woman's University School of Medicine, Seoul 07804, Korea.ORCID 0000-0002-0033-7805
Hyun-Joong KimDivision of Cardiology, Department of Medicine, Konkuk University Medical Center, Seoul 05030, Korea.ORCID 0000-0003-1636-0193
Jang-Whan BaeDepartment of Internal Medicine, Chungbuk National University College of Medicine, Cheongju 28644, Korea.
Sung Uk KwonDivision of Cardiology, Department of Internal Medicine, Ilsan Paik Hospital, University of Inje College of Medicine, Seoul 48108, Korea.ORCID 0000-0003-3435-3819
Hyun-Jong LeeDivision of Cardiology, Department of Medicine, Sejong General Hospital, Bucheon 14754, Korea.
Wang Soo LeeDivision of Cardiology, Department of Medicine, Chung-Ang University Hospital, Seoul 06973, Korea.ORCID 0000-0002-8264-0866
Sang-Don ParkDivision of Cardiology, Department of Medicine, Inha University Hospital, Incheon 22332, Korea.
Sung Soo ChoDivision of Cardiovascular Medicine, Department of Internal Medicine, Dankook University Hospital, Dankook University College of Medicine, Cheonan 31116, Korea.
Jae-Hyeong ParkDivision of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Daejeon 35015, Korea.ORCID 0000-0001-7035-286X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although inodilators (dobutamine and milrinone) are widely used empirically for cardiogenic shock (CS), the efficacy of inodilators for patients with CS undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is controversial. We evaluated the effects of inodilators on clinical outcomes using the RESCUE (REtrospective and prospective observational Study to investigate Clinical oUtcomes and Efficacy of left ventricular assist device for Korean patients with cardiogenic shock; NCT02985008) registry. We selected and analyzed the clinical outcomes of 496 patients who underwent VA-ECMO and did or did not receive inodilators. Of the 496 patients, 257 (51.8%) died during hospitalization. We selected 191 matched pairs to adjust for baseline clinical characteristics after 1:1 propensity score matching (PSM). The univariate and multivariate analyses showed that the inodilator group had significantly lower in-hospital mortality than the no-inodilator group (unadjusted hazard ratio [HR], 0.768; 95% confidence interval [CI], 0.579-1.018;

Indexed as

cardiogenic shockdobutamineextracorporeal membrane oxygenationmilrinone

Identifiers

PMID36078888
PMCPMC9456701

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.