Evidence map›Paper›PMID 36078743›Full record

ArticleInternational journal of environmental research and public health2022

The Role of Neighborhood Air Pollution Exposure on Somatic Non-Small Cell Lung Cancer Mutations in the Los Angeles Basin (2013-2018).

Noémie Letellier, Sam E Wing, Jiue-An Yang, Stacy W Gray, Tarik Benmarhnia, Loretta Erhunmwunsee, Marta M Jankowska

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. COPD-Lung Cancer Comorbidity: Mechanistic Insights and Precision Oncology Implications.International journal of chronic obstructive pulmonary disease · 2026
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noémie LetellierScripps Institution of Oceanography, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
Sam E WingDepartment of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
Jiue-An YangDepartment of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0003-4246-0470
Stacy W GrayDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
Tarik BenmarhniaScripps Institution of Oceanography, University of California San Diego, La Jolla, San Diego, CA 92093, USA.
Loretta ErhunmwunseeDepartment of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.ORCID 0000-0002-5847-9312
Marta M JankowskaDepartment of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.ORCID 0000-0002-8688-1181

Funding

Oncology Research Career Development ProgramK12CA001727 · NCI · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MORTIMER, JOANNE E. · 1992 to 2024
$14.6M
Integrating novel GIS and GPS data to assess the impact of built environments on changes in BMI, physical activity and cancer-related biomarkers in two successful weight loss interventions in women atR01CA228147 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BENMARHNIA, TARIK, JANKOWSKA, MARTA · 2019 to 2024
$2.6M
NCI NIH HHS K12 CA001727NCI NIH HHS R01 CA228147NCI NIH HHS R01CA228147
6 · The paper itself

Abstract

Limited previous work has identified a relationship between exposure to ambient air pollution and aggressive somatic lung tumor mutations. More work is needed to confirm this relationship, especially using spatially resolved air pollution. We aimed to quantify the association between different air pollution metrics and aggressive tumor biology. Among patients treated at City of Hope Comprehensive Cancer Center in Duarte, CA (2013-2018), three non-small cell lung cancer somatic tumor mutations,

Indexed as

Air PollutionCarcinoma, Non-Small-Cell LungLung NeoplasmsParticulate MatterAgedAir PollutantsEnvironmental ExposureFemaleHumansLos AngelesMutationNitrogen DioxideProto-Oncogene Proteins p21(ras)Air PollutantsNitrogen DioxideParticulate MatterProto-Oncogene Proteins p21(ras)machine learningNSCLCparticulate matterTP53 mutationtumor mutations

Identifiers

PMID36078743
PMCPMC9518136

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.