Evidence map›Paper›PMID 36078161›Full record

ArticleCells2022

Actin-Related Protein 4 and Linker Histone Sustain Yeast Replicative Ageing.

Mateusz Mołoń, Karolina Stępień, Patrycja Kielar, Bela Vasileva, Bonka Lozanska, Dessislava Staneva, Penyo Ivanov, Monika Kula-Maximenko, Eliza Molestak, Marek Tchórzewski and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Mateusz MołońDepartment of Biochemistry and Cell Biology, Institute of Biology and Biotechnology, University of Rzeszow, 35-601 Rzeszow, Poland.ORCID 0000-0002-9962-6788
Karolina StępieńDepartment of Biochemistry and Cell Biology, Institute of Biology and Biotechnology, University of Rzeszow, 35-601 Rzeszow, Poland.
Patrycja KielarDepartment of Biochemistry and Cell Biology, Institute of Biology and Biotechnology, University of Rzeszow, 35-601 Rzeszow, Poland.
Bela VasilevaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1123 Sofia, Bulgaria.ORCID 0000-0002-8718-6412
Bonka LozanskaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1123 Sofia, Bulgaria.
Dessislava StanevaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1123 Sofia, Bulgaria.ORCID 0000-0003-3518-6856
Penyo IvanovLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1123 Sofia, Bulgaria.
Monika Kula-MaximenkoThe Franciszek Górski Institute of Plant Physiology, Polish Academy of Sciences, 30-239 Kraków, Poland.ORCID 0000-0001-7100-877X
Eliza MolestakDepartment of Molecular Biology, Maria Curie-Skłodowska University, 20-033 Lublin, Poland.
Marek TchórzewskiDepartment of Molecular Biology, Maria Curie-Skłodowska University, 20-033 Lublin, Poland.ORCID 0000-0002-0718-4223
George MiloshevLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1123 Sofia, Bulgaria.ORCID 0000-0003-2979-8899
Milena GeorgievaLaboratory of Yeast Molecular Genetics, Institute of Molecular Biology "Acad. R. Tsanev", Bulgarian Academy of Sciences, 1123 Sofia, Bulgaria.ORCID 0000-0002-2371-7544
Bulgarian Academy of Sciences · BGUniversity of Rzeszów · PLMaria Curie-Skłodowska University · PLFranciszek Górski Institute of Plant Physiology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ageing is accompanied by dramatic changes in chromatin structure organization and genome function. Two essential components of chromatin, the linker histone Hho1p and actin-related protein 4 (Arp4p), have been shown to physically interact in

Indexed as

ActinsHistonesNuclear ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsChromatinTranscription FactorsActinsArp4 protein, S cerevisiaeChromatinHHO1 protein, S cerevisiaeHistonesNuclear ProteinsSaccharomyces cerevisiae ProteinsTranscription Factorsactin-related protein 4ageingArp4pHho1plinker histonereplicative lifespan

Identifiers

PMID36078161
PMCPMC9454676
OpenAlexW4294867034

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.