Evidence map›Paper›PMID 36078147›Full record

ArticleCells2022

Loss of Flocculus Purkinje Cell Firing Precision Leads to Impaired Gaze Stabilization in a Mouse Model of Spinocerebellar Ataxia Type 6 (SCA6).

Hui Ho Vanessa Chang, Anna A Cook, Alanna J Watt, Kathleen E Cullen

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Eye-head coordination during goal-directed orienting in mice.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hui Ho Vanessa ChangDepartment of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada.
Anna A CookDepartment of Biology, McGill University, Montreal, QC H3G 0B1, Canada.ORCID 0000-0001-7654-0212
Alanna J WattDepartment of Biology, McGill University, Montreal, QC H3G 0B1, Canada.ORCID 0000-0002-6371-6220
Kathleen E CullenDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
McGill University · CAJohns Hopkins University · US

Funding

The Physiology of Vestibular CompensationR01DC002390 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Kathleen E Cullen · 1995 to 2026
$10.7M
Neural Computations Underlying Cancellation of the Vestibular Consequences of Voluntary MovementR01DC018061 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Kathleen E Cullen · 2019 to 2026
$4.0M
Mechanism and Functional Significance of Polarity Reversal in Mechanosensory OrgansR01DC018304 · NIDCD · JACKSON LABORATORY · PI CULLEN, KATHLEEN E, EATOCK, RUTH ANNE · 2020 to 2024
$3.5M
A Neural Systems Approach to Understanding the Dynamic Computations Underlying our Sense of DirectionUF1NS111695 · NINDS · DARTMOUTH COLLEGE · PI TAUBE, JEFFREY STEVEN, VAN DER MEER, MATTHIJS · 2019 to 2019
$3.0M
NIDCD NIH HHS R01 DC002390NIDCD NIH HHS R01 DC018061NIDCD NIH HHS R01 DC018304NINDS NIH HHS UF1 NS111695
6 · The paper itself

Abstract

Spinocerebellar Ataxia Type 6 (SCA6) is a mid-life onset neurodegenerative disease characterized by progressive ataxia, dysarthria, and eye movement impairment. This autosomal dominant disease is caused by the expansion of a CAG repeat tract in the

Indexed as

Spinocerebellar AtaxiasSpinocerebellar DegenerationsAnimalsCerebellumDisease Models, AnimalMicePurkinje Cellseye movementsmotor learningoptokinetic reflexsaccadesspinocerebellar ataxia type 6vestibuloocular reflex

Identifiers

PMID36078147
PMCPMC9454745
OpenAlexW4294862315

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.