Evidence map›Paper›PMID 36078125›Full record

ArticleCells2022

Annexin A1-FPR2/ALX Signaling Axis Regulates Acute Inflammation during Chikungunya Virus Infection.

Simone de Araújo, Victor R de Melo Costa, Franciele M Santos, Carla D Ferreira de Sousa, Thaiane P Moreira, Matheus R Gonçalves, Franciel B Félix, Celso M Queiroz-Junior, Gabriel H Campolina-Silva, Maurício Lacerda Nogueira and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  6. Murine Models of Alphavirus Infection to Study the Immunopathogenesis of Pain.Methods in molecular biology (Clifton, N.J.) · 2026
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  13. Treatment with lipoxin AInflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
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  14. Impacts of CombiningInsects · 2024
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  15. Article
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  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 3 countries.

Simone de AraújoGraduate Program in Biological Sciences Physiology and Pharmacology, Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Victor R de Melo CostaDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Franciele M SantosDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Carla D Ferreira de SousaDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Thaiane P MoreiraDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Matheus R GonçalvesDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Franciel B FélixDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-2372-2781
Celso M Queiroz-JuniorDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Gabriel H Campolina-SilvaDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Maurício Lacerda NogueiraDepartment of Dermatological, Infections, and Parasitic Diseases, School of Medicine (FAMERP), São José do Rio Preto, São Paulo 15090-000, Brazil.ORCID 0000-0003-1102-2419
Michelle A SugimotoBarts and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London E1 4NS, UK.ORCID 0000-0002-4527-6065
Caio S BonilhaDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Mauro PerrettiBarts and The London School of Medicine and Dentistry, William Harvey Research Institute, Queen Mary University of London, London E1 4NS, UK.ORCID 0000-0003-2068-3331
Danielle G SouzaGraduate Program in Microbiology, Department of Microbiology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-7478-5934
Vivian V CostaDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.ORCID 0000-0002-0175-642X
Mauro M TeixeiraDrug Research and Development Center, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte 31270-901, Brazil.
Universidade Federal de Minas Gerais · BRQueen Mary University of London · GBFaculdade de Medicina de São José do Rio Preto · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chikungunya (CHIKV) is an arthritogenic alphavirus that causes a self-limiting disease usually accompanied by joint pain and/or polyarthralgia with disabling characteristics. Immune responses developed during the acute phase of CHIKV infection determine the rate of disease progression and resolution. Annexin A1 (

Indexed as

Chikungunya FeverInflammationAdaptor Proteins, Signal TransducingAnimalsAnnexin A1ArthralgiaMiceMice, KnockoutReceptors, Formyl PeptideAdaptor Proteins, Signal TransducingAnnexin A1formyl peptide receptor 2, mouseHSH2 protein, mouseReceptors, Formyl PeptideAc2–26 peptideAnnexin-A1CHIKVFPR2neutrophils

Identifiers

PMID36078125
PMCPMC9454528
OpenAlexW4294142667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.