Evidence map›Paper›PMID 36078073›Full record

ReviewCells2022

Applications of CRISPR/Cas13-Based RNA Editing in Plants.

Naga Rajitha Kavuri, Manikandan Ramasamy, Yiping Qi, Kranthi Mandadi

Abstract readReview
In one paragraph

Review in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. From Lab to Field: CRISPRing Major CultivatedInternational journal of molecular sciences · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. CRISPR-Cas Gene Editing Technology in Potato.International journal of molecular sciences · 2025
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Naga Rajitha KavuriTexas A&M AgriLife Research and Extension Center, Texas A&M University System, 2415 E. Highway 83, Weslaco, TX 78596, USA.
Manikandan RamasamyTexas A&M AgriLife Research and Extension Center, Texas A&M University System, 2415 E. Highway 83, Weslaco, TX 78596, USA.ORCID 0000-0003-1788-241X
Yiping QiDepartment of Plant Science and Landscape Architecture, University of Maryland, College Park, MD 20742, USA.
Kranthi MandadiTexas A&M AgriLife Research and Extension Center, Texas A&M University System, 2415 E. Highway 83, Weslaco, TX 78596, USA.ORCID 0000-0003-2986-4016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated (Cas) system is widely used as a genome-editing tool in various organisms, including plants, to elucidate the fundamental understanding of gene function, disease diagnostics, and crop improvement. Among the CRISPR/Cas systems, Cas9 is one of the widely used nucleases for DNA modifications, but manipulation of RNA at the post-transcriptional level is limited. The recently identified type VI CRISPR/Cas systems provide a platform for precise RNA manipulation without permanent changes to the genome. Several studies reported efficient application of Cas13 in RNA studies, such as viral interference, RNA knockdown, and RNA detection in various organisms. Cas13 was also used to produce virus resistance in plants, as most plant viruses are RNA viruses. However, the application of CRISPR/Cas13 to studies of plant RNA biology is still in its infancy. This review discusses the current and prospective applications of CRISPR/Cas13-based RNA editing technologies in plants.

Indexed as

CRISPR-Cas SystemsRNA EditingGene EditingPlantsRNARNACRISPR/Cas13RNA editingRNA interferenceRNA targetingtype VI CRISPR systems

Identifiers

PMID36078073
PMCPMC9454418

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.