Evidence map›Paper›PMID 36078047›Full record

ArticleCells2022

The ADP-Ribosylation Factor 4d Restricts Regulatory T-Cell Induction via Control of IL-2 Availability.

Bernd Geers, Julia Hagenstein, Jessica Endig, Hanna Ulrich, Laura Fleig, Paulina Sprezyna, Julita Mikulec, Lukas Heukamp, Gisa Tiegs, Linda Diehl

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Bernd GeersInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Julia HagensteinInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Jessica EndigInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Hanna UlrichInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Laura FleigInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Paulina SprezynaInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Julita MikulecInstitute of Experimental Medicine, University Hospital Bonn, 53127 Bonn, Germany.
Lukas HeukampInstitute for Hematopathology, 22547 Hamburg, Germany.ORCID 0000-0002-3388-3482
Gisa TiegsInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Linda DiehlInstitute of Experimental Immunology and Hepatology, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Universität Hamburg · DEInstitut für Hämatopathologie Hamburg · DEUniversity Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-2 is central to the induction and maintenance of both natural (nT

Indexed as

Interleukin-2T-Lymphocytes, RegulatoryADP-Ribosylation FactorsAnimalsForkhead Transcription FactorsMiceMice, KnockoutTransforming Growth Factor betaADP-Ribosylation FactorsArl4D protein, mouseForkhead Transcription FactorsInterleukin-2Transforming Growth Factor betaArl4dFoxp3immune regulationinterleukin 2pSTAT5regulatory T cell

Identifiers

PMID36078047
PMCPMC9454872
OpenAlexW4293104234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.