Evidence map›Paper›PMID 36078040›Full record

ArticleCells2022

Genetic Mouse Models to Study Pancreatic Cancer-Induced Pain and Reduction in Well-Being.

Michael Hirth, Yong Xie, Christiane Höper, Amandine Prats, Thilo Hackert, Matthias P Ebert, Rohini Kuner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Michael HirthPharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Yong XiePharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Christiane HöperPharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-3465-8869
Amandine PratsPharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.ORCID 0000-0002-2125-366X
Thilo HackertDepartment of General, Visceral and Transplantation Surgery, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Matthias P EbertDepartment of Medicine II, Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany.
Rohini KunerPharmacology Institute, Medical Faculty Heidelberg, Heidelberg University, 69120 Heidelberg, Germany.
Heidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In addition to the poor prognosis, excruciating abdominal pain is a major challenge in pancreatic cancer. Neurotropism appears to be the underlying mechanism leading to neuronal invasion. However, there is a lack of animal models suitable for translationally bridging in vitro findings with clinical trials. We characterized KPC (Kras

Indexed as

Cancer PainPancreatic NeoplasmsAbdominal PainAnimalsCytokinesDisease Models, AnimalHumansMiceProto-Oncogene Proteins p21(ras)CytokinesProto-Oncogene Proteins p21(ras)cytokinesKPCKPPCnerve hypertrophypainpancreatic ductal adenocarcinoma

Identifiers

PMID36078040
PMCPMC9454877
OpenAlexW4293010208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.