Evidence map›Paper›PMID 36078001›Full record

ArticleAnimals : an open access journal from MDPI2022

Dietary Garlic Powder Alleviates Lipopolysaccharide-Induced Inflammatory Response and Oxidative Stress through Regulating the Immunity and Intestinal Barrier Function in Broilers.

Ruiqiang Zhang, Jinsong Liu, Yulan Liu, Yanping Wu, Yinglei Xu, Jie Feng

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Potential Effects of Garlic (Animals : an open access journal from MDPI · 2024
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ruiqiang ZhangCollege of Animal Science, Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Zhejiang University, Hangzhou 310058, China.ORCID 0000-0001-6464-943X
Jinsong LiuKey Agricultural Research Institute of Green Animal Health Products of Zhejiang Province, Zhejiang Vegamax Biotechnology Co., Ltd., Huzhou 313300, China.
Yulan LiuKey Agricultural Research Institute of Green Animal Health Products of Zhejiang Province, Zhejiang Vegamax Biotechnology Co., Ltd., Huzhou 313300, China.
Yanping WuCollege of Animal Science and Technology, College of Veterinary Medicine, Zhejiang Agricultural and Forestry University, Hangzhou 311300, China.
Yinglei XuCollege of Animal Science and Technology, College of Veterinary Medicine, Zhejiang Agricultural and Forestry University, Hangzhou 311300, China.ORCID 0000-0001-7375-7969
Jie FengCollege of Animal Science, Key Laboratory of Animal Feed and Nutrition of Zhejiang Province, Zhejiang University, Hangzhou 310058, China.
Zhejiang A & F University · CNZhejiang University · CN

Funding

Foundation of Key Laboratory of Animal Feed and Nutrition of Zhejiang Province 202109Zhejiang Province Key Agricultural Research Institute of Green Animal Health Products Project 2021Y30004Zhejiang Provincial Key R&D Program of China 2021C02008Zhejiang Provincial Leading Innovation and Entrepreneurship Team Project 2020R01015
6 · The paper itself

Abstract

Garlic powder (GP) has the outstanding antibacterial, antifungal, antiviral, anti-parasitic and antioxidant characteristics because of its various contained bioactive components, such as alliin, allicin, and polysaccharide, etc. It has been widely used as a native medicine and shown to prevent a variety of diseases. This research was performed to determine the positive effects of GP on growth and intestinal function in lipopolysaccharide (LPS) challenged broilers. A total of 480 one-day-old male Ross 308 broilers of similar initial body weight were randomly divided into four groups with 8 replicates per treatment and 15 chicks each replicate. LPS challenge enhanced the weight loss rate, decreased the immunity and antioxidant capability, increased the intestinal permeability in broilers. When compared with LPS group, broilers fed with GP exhibited improved weight loss rate and jejunum villus height, enhanced ileum antioxidant function, and ameliorated intestinal barrier function. The LPS-challenged broilers in GP group had higher immunity than that of broilers in antibiotics group. GP supplementation could act as a natural alternative to antibiotic additive to alleviate the LPS-induced weight loss rate, inflammatory responses, and oxidative stress in broilers by improving the immunity and intestinal function.

Indexed as

broilergarlic powderinflammatory responseintestinal barrier functionlipopolysaccharide

Identifiers

PMID36078001
PMCPMC9454656
OpenAlexW4294983495

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.