ArticleAnimals : an open access journal from MDPI2022
Effect of Chinese Herbs on Serum Biochemical Parameters, Immunity Indices, Antioxidant Capacity and Metabolomics in Early Weaned Yak Calves.
Article in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 10 citations in OpenAlex.
- Wuwei Jianpi San Improves Growth Performance and Immune Status in Yaks Through Modulation of Rumen Microbiota and Host Metabolism.Animals : an open access journal from MDPI · 2026Article
- Mixed silage of sweet sorghum and aerial parts of licorice modulate growth, rumen function, and microbial profiles in Karakul sheep.Frontiers in microbiology · 2026Article
- Effects of glycyrrhetinic acid on production performance, serum biochemical indexes, ruminal parameters, and rumen microflora of beef cattle.Frontiers in veterinary science · 2025Article
- Article
- The biological functions ofFrontiers in veterinary science · 2025Review
- Licorice Extract Supplementation Benefits Growth Performance, Blood Biochemistry and Hormones, Immune Antioxidant Status, Hindgut Fecal Microbial Community, and Metabolism in Beef Cattle.Veterinary sciences · 2024Article
- Effects of feeding different proportions of steam-flaked corn-based starter on growth performance, immunity and serum metabolism of pre-weaned Simmental calves.Frontiers in veterinary science · 2024Article
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Authors and funding
5 authors at 5 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Chinese traditional herbs are used widely as feed supplements to improve the immune response and antioxidant capacity of livestock. Twenty early-weaned 4-month-old yak calves (72.3 ± 3.65 kg) were divided randomly into four groups (n = 5 per group); three groups were provided with supplementary 80 mL/kg DMI of the root water extracts of either Angelica sinensis, Codonopsis pilosula or Glycyrrhiza uralensis, and one group (control) was not provided with a supplement. Compared to control calves, calves consuming the three herbal extracts increased serum concentrations of albumin (ALB) and glutathione peroxidase (GSH-Px), but decreased serum concentrations of free fatty acids (FFAs) and malondialdehyde (MDA) (p < 0.05). Calves consuming A. sinensis decreased (p < 0.05) serum concentration of total cholesterol (TC), and increased (p < 0.05) serum concentration of total proteins (TP). Serum FFA concentrations increased (p = 0.004) linearly with time in the control group, but not in the groups consuming herbs. Serum metabolomic data demonstrated that A. sinensis and C. pilosula regulate mainly amino acid metabolism, while G. uralensis regulates mainly carbon and amino acid metabolism. It was concluded that the three herbal root extracts, as dietary supplements, improved energy and nitrogen metabolism, and enhanced the antioxidant capacity of yak calves.
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