ReviewCancers2022
Complications of Immediate versus Delayed DIEP Reconstruction: A Meta-Analysis of Comparative Studies.
Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 22 citations in OpenAlex.
- Deep Inferior Epigastric Perforator Flap Reconstruction Outcomes Across Body Mass Index Categories: A Retrospective Study.Plastic and reconstructive surgery. Global open · 2026Article
- Balancing Risk and Reconstruction: A Comprehensive Review of Complications in Delayed Breast Reconstruction.Journal of clinical medicine · 2026Review
- PAP Versus DIEP Flap Breast Reconstruction: Current Evidence and the Unresolved Question of Timing and Oncologic Safety-A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Clinical and Functional Outcomes Following Reverse Sural Flap of Lower Extremity Defects: A Comparative Retrospective Study.Clinics in orthopedic surgery · 2026Article
- Impact of Previous Abdominal Surgery on Postoperative Complication of Deep Inferior Epigastric Perforator Flap Breast Reconstruction: A Retrospective Comparative Study.Plastic and reconstructive surgery. Global open · 2025Article
- Pushing the DIEP Envelope: Where Are We Now?Journal of clinical medicine · 2025Review
- Breast reconstruction and neoadjuvant radiotherapy (BRENAR) - study protocol for a multicenter, prospective, single-arm pilot study.International journal of surgery protocols · 2025Article
- The Impact of Hormonal Therapy on Autologous Microvascular Breast Reconstruction: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Complications of Prosthetic Breast Reconstruction in Prophylactic Versus Therapeutic Mastectomy: A Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Deep Inferior Epigastric Perforator Flap Breast Reconstruction in Patients With or Without Previous Abdominal Surgery: A Systemic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2025Article
- Nerve coaptation in deep inferior epigastric perforator (DIEP) flap breast reconstruction.Gland surgery · 2025Article
- Analysis of Postoperative Outcomes in Unilateral Versus Bilateral DIEP Flap Reconstructions: A Single-Center Retrospective Study.Journal of clinical medicine · 2025Article
- Article
- Outcomes and Current State of Deep Inferior Epigastric Perforator Flap Surgery in Peru and Mexico.Plastic and reconstructive surgery. Global open · 2025Article
- Outcomes and Complications of Implant-Based Breast Reconstruction in Patients With Previous Cosmetic Augmentation: A Systematic Review.Aesthetic surgery journal. Open forum · 2025Review
- A Meta-analysis Comparing Deep Inferior Epigastric Perforator Flaps and Latissimus Dorsi Flaps in Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2024Article
- Unveiling Intricacies of DIEP Breast Reconstruction Post Early Breast Cancer: A Deep Dive into a Case of Unforeseen Complications.Cancer management and research · 2024Article
- Technical consideration for breast reconstruction in patients requiring neoadjuvant or adjuvant radiotherapy: a narrative review.Annals of translational medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe setting regarding the ideal timing for deep inferior epigastric perforator flap (DIEP) reconstruction remains unclear. Immediate breast reconstruction (IBR) is performed at the same time as mastectomy, while delayed breast reconstruction (DBR) is performed at any time after mastectomy except immediately. We compared both strategies to assess whether IBR or DBR should be performed to reduce postoperative adverse events.
methodsA systematic review of PubMed, Embase, Medline, Cochrane, and Web of Science was conducted, aiming at articles comparing the recipient site outcomes of IBR versus DBR with DIEP. We used the Mantel-Haenszel method with a fixed effects model. Results were expressed as the OR with a 95% CI.
resultsTwo retrospective and two prospective studies were identified involving 5784 DIEPs (1744 immediate and 4040 delayed). We showed a significant difference in favor of IBR for wound healing issues (OR = 0.57, 95% CI 0.41, 0.77;
conclusionsDespite variability in the choice of the ideal time for breast reconstruction and outcomes reported among studies, immediate DIEP surgery appears to be a reliable setting with less delayed healing issues.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.