Evidence map›Paper›PMID 36077788›Full record

ArticleCancers2022

FAP-Specific Signalling Is an Independent Diagnostic Approach in ACC and Not a Surrogate Marker of MRI Sequences.

Dawn P Liew, Manuel Röhrich, Lisa Loi, Sebastian Adeberg, Mustafa Syed, Ewgenija Gutjahr, Heinz Peter Schlemmer, Frederik L Giesel, Martin Bendszus, Uwe Haberkorn and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Case report: [American journal of nuclear medicine and molecular imaging · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Dawn P LiewDepartment of Nuclear Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0002-9200-2470
Manuel RöhrichDepartment of Nuclear Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Lisa LoiDivision of Radiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Sebastian AdebergDepartment of Radiation Oncology, University Hospital Heidelberg, 69120 Heidelberg, Germany.ORCID 0000-0001-8463-514X
Mustafa SyedDepartment of Radiation Oncology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Ewgenija GutjahrDepartment of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Heinz Peter SchlemmerDivision of Radiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Frederik L GieselDepartment of Nuclear Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Martin BendszusDepartment of Neuroradiology, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Uwe HaberkornDepartment of Nuclear Medicine, University Hospital Heidelberg, 69120 Heidelberg, Germany.
Daniel PaechDivision of Radiology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Heidelberg University · DEGerman Cancer Research Center · DE

Funding

Federal Ministry of Education and Research 13N 13341.
6 · The paper itself

Abstract

backgroundFibroblast Activation Protein (FAP) is a new target for positron emission tomography and computed tomography (PET/CT) imaging of epithelial tumours embedded in a fibrous stroma. Adenoid cystic carcinomas (ACCs) have shown elevated tracer uptake in

methodsClinical PET/CT scans of 12 ACC patients were performed at 10, 60 and 180 min post i.v. administration of

results

conclusionThere are only slight correlations between the intensity of

Indexed as

ACCadenoid cystic carcinomaFAPfibroblast activation proteinMRIpixelwise correlationpositron emission tomography

Identifiers

PMID36077788
PMCPMC9454795
OpenAlexW4294343984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.