Evidence map›Paper›PMID 36077782›Full record

ArticleCancers2022

Improved Survival of Lymphoma Patients with COVID-19 in the Modern Treatment and Vaccination Era.

Alexandra Della Pia, Charles Zhao, Parul Jandir, Amolika Gupta, Mark Batistick, Gee Youn Geeny Kim, Yi Xia, Jaeil Ahn, Gabriella Magarelli, Brittany Lukasik and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Alexandra Della PiaHackensack University Medical Center, Hackensack, NJ 07601, USA.
Charles ZhaoHackensack Meridian School of Medicine, Nutley, NJ 07110, USA.ORCID 0000-0002-7843-2220
Parul JandirHackensack Meridian School of Medicine, Nutley, NJ 07110, USA.
Amolika GuptaHackensack Meridian School of Medicine, Nutley, NJ 07110, USA.
Mark BatistickHackensack Meridian School of Medicine, Nutley, NJ 07110, USA.
Gee Youn Geeny KimHackensack University Medical Center, Hackensack, NJ 07601, USA.ORCID 0000-0001-8145-3017
Yi XiaDepartment of Biostatistics, Bioninformatics, and Biomathematics, Georgetown University, Washington, DC 20057, USA.
Jaeil AhnDepartment of Biostatistics, Bioninformatics, and Biomathematics, Georgetown University, Washington, DC 20057, USA.ORCID 0000-0001-7998-4759
Gabriella MagarelliHackensack University Medical Center, Hackensack, NJ 07601, USA.
Brittany LukasikHackensack University Medical Center, Hackensack, NJ 07601, USA.
Lori A LeslieHackensack University Medical Center, Hackensack, NJ 07601, USA.
Andre H GoyHackensack University Medical Center, Hackensack, NJ 07601, USA.
Andrew IpHackensack University Medical Center, Hackensack, NJ 07601, USA.ORCID 0000-0003-0456-5618
Tatyana A FeldmanHackensack University Medical Center, Hackensack, NJ 07601, USA.
Hackensack University Medical Center · USCenter for Discovery · USGeorgetown University · USRutgers, The State University of New Jersey · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoma patients are at greater risk of severe consequences from COVID-19 infection, yet most reports of COVID-19-associated outcomes were published before the advent of COVID-19 vaccinations and monoclonal antibodies (mAbs). In this retrospective study, we report the real-world outcomes of 68 lymphoma or CLL patients who developed COVID-19 infection during the omicron surge in the US. We found that 34% of patients were hospitalized as a result of COVID-19 infection. The death rate due to COVID-19 was 9% (6/68) in the overall population and 26% (6/23) in hospitalized patients. During the preintervention COVID-19 era, the mortality rate reported in cancer patients was 34%, which increased to 60.2% in hospitalized patients. Thus, the death rates in our study were much lower when compared to those in cancer patients earlier in the pandemic, and may be attributed to modern interventions. In our study, 60% (18/30) of patients with serology data available did not develop anti-COVID-19 spike protein antibodies following vaccination. Most patients (74%, 17/23) who were hospitalized due to COVID-19 infection did not receive COVID-19 mAb treatment. Our results pointed to the importance of humoral immunity and the protective effect of COVID-19 mAbs in improving outcomes in lymphoma patients.

Indexed as

COVID-19lymphomamonoclonal antibodiesomicronvaccines

Identifiers

PMID36077782
PMCPMC9454633
OpenAlexW4294343803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.