Evidence map›Paper›PMID 36077769›Full record

ReviewCancers2022

Novel Insights into miR-944 in Cancer.

Jinze Shen, Qurui Wang, Chenhao Liang, Xinming Su, Yufei Ke, Yunan Mao, Jie Fang, Shiwei Duan

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. miRNA-Seq Tissue Diagnostic Signature: A Novel Model for NSCLC Subtyping.International journal of molecular sciences · 2023
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jinze ShenDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.
Qurui WangDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.
Chenhao LiangDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.
Xinming SuDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.
Yufei KeDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.
Yunan MaoDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.ORCID 0000-0002-5466-0886
Jie FangDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.ORCID 0000-0003-2881-4033
Shiwei DuanDepartment of Clinical Medicine, Zhejiang University City College School of Medicine, Hangzhou 310015, China.ORCID 0000-0001-7682-2877
Zhejiang University · CN

Funding

the Science and Technology Development Program of Hangzhou 20140633B39
6 · The paper itself

Abstract

miRNA is a class of endogenous short-chain non-coding RNAs consisting of about 22 nucleotides. miR-944 is located in the fourth intron of the TP63 gene in the 3q28 region. miR-944 is abnormally expressed in cancers in multiple systems including neural, endocrine, respiratory, reproductive, and digestive systems. miR-944 can target at least 27 protein-coding genes. miR-944 can regulate a series of cell behaviors, such as cell cycle, proliferation, invasion and migration, EMT, apoptosis, etc. miR-944 participates in the networks of 11 ceRNAs, including six circRNAs and five lncRNAs. miR-944 is involved in three signaling pathways. The abnormal expression of miR-944 is closely related to the clinicopathological conditions of various cancer patients. Deregulated expression of miR-944 is significantly associated with clinicopathology and prognosis in cancer patients. In addition, miR-944 is also associated with the development of DDP, RAPA, DOX, and PTX resistance in cancer cells. miR-944 is involved in the anticancer molecular mechanisms of matrine and Rhenium-liposome drugs. In conclusion, this work systematically summarizes the related findings of miR-944, which will provide potential hints for follow-up research on miR-944.

Indexed as

ceRNAdiagnosisdrugdysregulationmiR-944prognosis

Identifiers

PMID36077769
PMCPMC9454979
OpenAlexW4294142588

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.