ArticleCancers2022
As Easy as 1, 2, 3? How to Determine CBCT Frequency in Adjuvant Breast Radiotherapy.
Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed.
- The impact of orthogonal image-guided frequency on positioning error correction and dose in postoperative radiotherapy for breast cancer.BMC cancer · 2026Article
- Optimization of CBCT-guided imaging schedules for left-sided postmastectomy radiotherapy using VMAT: A dosimetric, radiobiological, and cost analysis.Journal of applied clinical medical physics · 2026Article
- Beyond the snapshot: continuous optical surface monitoring reveals non-linear temporal dynamics and postural stability window in free-breathing breast radiotherapy.Frontiers in oncology · 2026Article
- Optimal fractionation and timing of weekly cone-beam CT in daily surface-guided radiotherapy for breast cancer.Radiation oncology (London, England) · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study aims to assess the suitability of setup errors during the first three treatment fractions to determine cone-beam computed tomography (CBCT) frequency in adjuvant breast radiotherapy. For this, 45 breast cancer patients receiving non-hypofractionated radiotherapy after lumpectomy, including a simultaneous integrated boost (SIB) to the tumor bed and daily CBCT imaging, were retrospectively selected. In a first step, mean and maximum setup errors on treatment days 1-3 were correlated with the mean setup errors during subsequent treatment days. In a second step, dose distribution was estimated using a dose accumulation workflow based on deformable image registration, and setup errors on treatment days 1-3 were correlated with dose deviations in the clinical target volumes (CTV) and organs at risk (OAR). No significant correlation was found between mean and maximum setup errors on treatment days 1-3 and mean setup errors during subsequent treatment days. In addition, mean and maximum setup errors on treatment days 1-3 correlated poorly with dose coverage of the CTVs and dose to the OARs. Thus, CBCT frequency in adjuvant breast radiotherapy should not be determined solely based on the magnitude of setup errors during the first three treatment fractions.
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Registered trials
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