Evidence map›Paper›PMID 36077648›Full record

ReviewCancers2022

Treatment of Recurrent Nasopharyngeal Carcinoma: A Sequential Challenge.

Zhouying Peng, Yumin Wang, Ruohao Fan, Kelei Gao, Shumin Xie, Fengjun Wang, Junyi Zhang, Hua Zhang, Yuxiang He, Zhihai Xie and 1 more

Abstract readReview
In one paragraph

Review in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
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  7. Role of PANoptosis in cancer: Molecular mechanisms and therapeutic opportunities.Apoptosis : an international journal on programmed cell death · 2025
    Review
  8. Review
  9. Review
  10. Article
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  12. Article
  13. Article
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  15. [Research progress on the role and mechanism of IGF2BPs family in head and neck squamous carcinoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2024
    Review
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhouying PengDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Yumin WangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Ruohao FanDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Kelei GaoDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Shumin XieDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Fengjun WangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Junyi ZhangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Hua ZhangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Yuxiang HeNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha 410008, China.
Zhihai XieDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Weihong JiangDepartment of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.

Funding

National Natural Science Foundation of China 82171118
6 · The paper itself

Abstract

Recurrent nasopharyngeal carcinoma (NPC), which occurs in 10-20% of patients with primary NPC after the initial treatment modality of intensity-modulated radiation therapy (IMRT), is one of the major causes of death among NPC patients. Patients with recurrent disease without distant metastases still have a chance to be saved, but re-treatment often carries more serious toxicities or higher risks. For this group of patients, both otolaryngologists and oncologists are committed to developing more appropriate treatment regimens that can prolong patient survival and improve survival therapy. Currently, there are no international guidelines for the treatment of patients with recurrent NPC. In this article, we summarize past publications on clinical research and mechanistic studies related to recurrent NPC, combined with the experience and lessons learned by our institutional multidisciplinary team in the treatment of recurrent NPC. We propose an objective protocol for the treatment of recurrent NPC.

Indexed as

biomarkersmanagementnasopharyngeal carcinomarecurrenttreatment modality

Identifiers

PMID36077648
PMCPMC9454547

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.