Evidence map›Paper›PMID 36077570›Full record

ArticleInternational journal of molecular sciences2022

Trifuhalol A Suppresses Allergic Inflammation through Dual Inhibition of TAK1 and MK2 Mediated by IgE and IL-33.

Sim-Kyu Bong, No-June Park, Sang Heon Lee, Jin Woo Lee, Aaron Taehwan Kim, Xiaoyong Liu, Sang Moo Kim, Min Hye Yang, Yong Kee Kim, Su-Nam Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Anti-Allergic Inflammatory Effect ofCurrent issues in molecular biology · 2023
    Article
  4. Article
  5. Trifuhalol A, a phlorotannin from the brown algaeCurrent research in food science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Sim-Kyu BongNatural Products Research Institute, Korea Institute of Sceience and Technology (KIST), Gangneung 25451, Korea.
No-June ParkNatural Products Research Institute, Korea Institute of Sceience and Technology (KIST), Gangneung 25451, Korea.
Sang Heon LeeNatural Products Research Institute, Korea Institute of Sceience and Technology (KIST), Gangneung 25451, Korea.
Jin Woo LeeNatural Products Research Institute, Korea Institute of Sceience and Technology (KIST), Gangneung 25451, Korea.
Aaron Taehwan KimDepartment of Food Science, University of Massachusetts, Amherst, MA 01003, USA.
Xiaoyong LiuHaizhibao Deutschland GmbH, Heiliggeistgasse 28, 85354 Freising, Germany.
Sang Moo KimDepartment of Marine Food Science and Technology, Gangneung-Wonju National University, 7 Jukheon-gil, Gangneung 25457, Korea.
Min Hye YangCollege of Pharmacy, Pusan National University, Busan 46241, Korea.
Yong Kee KimCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.ORCID 0000-0002-6413-7538
Su-Nam KimNatural Products Research Institute, Korea Institute of Sceience and Technology (KIST), Gangneung 25451, Korea.
Gangneung–Wonju National University · KRKorea Institute of Science and Technology · KRBio-Medical Science (South Korea) · KRSookmyung Women's University · KRUniversity of Massachusetts Amherst · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The activation and degranulation of immune cells play a pivotal role in allergic inflammation, a pathological condition that includes anaphylaxis, pruritus, and allergic march-related diseases. In this study, trifuhalol A, a phlorotannin isolated from

Indexed as

AnaphylaxisDermatitis, AtopicAnimalsCytokinesImmunoglobulin EInflammationInterleukin-33Mast CellsMicep-Methoxy-N-methylphenethylaminePruritusPyroglyphidaeCytokinesImmunoglobulin EInterleukin-33p-Methoxy-N-methylphenethylamineallergic inflammationdegranulationimmunoglobulin Einterleukin-33MAPK-activated protein kinase 2TGFβ-activated kinase 1trifuhalol A

Identifiers

PMID36077570
PMCPMC9456157
OpenAlexW4294733750

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.