Evidence map›Paper›PMID 36077478›Full record

ReviewInternational journal of molecular sciences2022

A Narrative Review of the Association between Obstructive Sleep Apnea and Glaucoma in Adults.

Barbara Leggewie, Haralampos Gouveris, Katharina Bahr

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. A pilot study of body-mind-spirit group therapy on sleep and quality of life in individuals with visual impairment.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Barbara LeggewieDepartment of Otorhinolaryngology, Head and Neck Surgery, University Hospital Bonn, 53127 Bonn, Germany.
Haralampos GouverisDepartment of Otolaryngology, Head and Neck Surgery, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7299-7346
Katharina BahrDepartment of Otolaryngology, Head and Neck Surgery, University Medical Center Mainz, 55131 Mainz, Germany.ORCID 0000-0001-7428-127X
Johannes Gutenberg University Mainz · DEUniversity Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObstructive sleep apnea (OSA) is a sleep disorder, primarily of the upper airway, which not only has a significant impact on quality of life but is also associated with various systemic diseases. Several ophthalmological diseases are also associated with OSA, especially glaucoma. The purpose of this review is to take a closer look at the causality and mutual influence.

methodsA systematic literature search was conducted using PubMed. A total of 19 studies with 316,178 adult participants were included.

resultsEleven of the sixteen studies concentrating on the prevalence of glaucoma in patients with OSA showed an association of both entities. One paper found a higher risk for progression of glaucoma in OSA patients. Five of the sixteen included studies failed to show a correlation between OSA and glaucoma. One study out of three surveying specific ophthalmological parameters showed an influence of OSA therapy on retinal nerve fiber layer (RNFL) thinning and vision. One study showed a rise in intraocular pressure (IOP), while two other studies showed no increase under continuous positive airway pressure (CPAP).

conclusionsOur findings suggest an association between OSA and glaucoma and, especially, between OSA and thinning of RNFL. CPAP therapy appears to be also suitable for patients with comorbid glaucoma.

Indexed as

GlaucomaSleep Apnea, ObstructiveAdultContinuous Positive Airway PressureHumansIntraocular PressureQuality of LifeAHIglaucomaobstructive sleep apneaRNFLsleep-disordered breathing

Identifiers

PMID36077478
PMCPMC9456240
OpenAlexW4294733122

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.