Evidence map›Paper›PMID 36077451›Full record

ArticleInternational journal of molecular sciences2022

Novel Short PEG Chain-Substituted Porphyrins: Synthesis, Photochemistry, and In Vitro Photodynamic Activity against Cancer Cells.

Dawid Lazewski, Malgorzata Kucinska, Edward Potapskiy, Joanna Kuzminska, Artur Tezyk, Lukasz Popenda, Stefan Jurga, Anna Teubert, Zofia Gdaniec, Jacek Kujawski and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Dawid LazewskiDepartment of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.ORCID 0000-0002-9832-5094
Malgorzata KucinskaDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30 Street, 60-631 Poznan, Poland.ORCID 0000-0002-3606-3623
Edward PotapskiyDepartment of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
Joanna KuzminskaDepartment of Pharmaceutical Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.ORCID 0000-0002-8514-5238
Artur TezykDepartment of Forensic Medicine, Poznan University of Medical Sciences, Swiecickiego 6 Street, 60-781 Poznan, Poland.
Lukasz PopendaNanoBioMedical Centre, Adam Mickiewicz University in Poznan, Wszechnicy Piastowskiej 3 Street, 61-614 Poznan, Poland.ORCID 0000-0003-1117-3081
Stefan JurgaNanoBioMedical Centre, Adam Mickiewicz University in Poznan, Wszechnicy Piastowskiej 3 Street, 61-614 Poznan, Poland.ORCID 0000-0002-1665-6077
Anna TeubertInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Street, 61-704 Poznan, Poland.
Zofia GdaniecInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Street, 61-704 Poznan, Poland.ORCID 0000-0003-2955-1829
Jacek KujawskiDepartment of Organic Chemistry, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.ORCID 0000-0001-6279-4887
Katarzyna GrzybFaculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 8 Street, 61-614 Poznan, Poland.ORCID 0000-0002-7035-3456
Tomasz PedzinskiFaculty of Chemistry, Adam Mickiewicz University in Poznan, Uniwersytetu Poznanskiego 8 Street, 61-614 Poznan, Poland.
Marek MuriasDepartment of Toxicology, Poznan University of Medical Sciences, Dojazd 30 Street, 60-631 Poznan, Poland.ORCID 0000-0002-2903-4912
Marcin WierzchowskiDepartment of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6 Street, 60-780 Poznan, Poland.
Poznan University of Medical Sciences · PLAdam Mickiewicz University in Poznań · PLInstitute of Bioorganic Chemistry, Polish Academy of Sciences · PL

Funding

National Science Center UMO-2021/43/B/NZ7/02476
6 · The paper itself

Abstract

This work presents the synthesis and characterization of metal-free, zinc (II), and cobalt (II) porphyrins substituted with short PEG chains. The synthesized compounds were characterized by UV-Vis,

Indexed as

Antineoplastic AgentsNeoplasmsPhotochemotherapyPorphyrinsHumansPhotochemistryPhotosensitizing AgentsZincAntineoplastic AgentsPhotosensitizing AgentsPorphyrinsZinccancer cellsphotodynamic therapypolyethylene glycolporphyrinssinglet oxygen

Identifiers

PMID36077451
PMCPMC9456001
OpenAlexW4294739274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.