Evidence map›Paper›PMID 36077439›Full record

ArticleInternational journal of molecular sciences2022

Ligand-Based Virtual Screening and Molecular Docking of Benzimidazoles as Potential Inhibitors of Triosephosphate Isomerase Identified New Trypanocidal Agents.

Lenci K Vázquez-Jiménez, Alfredo Juárez-Saldivar, Rogelio Gómez-Escobedo, Timoteo Delgado-Maldonado, Domingo Méndez-Álvarez, Isidro Palos, Debasish Bandyopadhyay, Carlos Gaona-Lopez, Eyra Ortiz-Pérez, Benjamín Nogueda-Torres and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

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  5. A Computational Approach Using α-Carbonic Anhydrase to Find Anti-Medicinal chemistry (Shariqah (United Arab Emirates)) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Lenci K Vázquez-JiménezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0002-9327-9658
Alfredo Juárez-SaldivarLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0002-4059-7361
Rogelio Gómez-EscobedoEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México 11340, Mexico.
Timoteo Delgado-MaldonadoLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Domingo Méndez-ÁlvarezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Isidro PalosUnidad Académica Multidisciplinaria Reynosa-Rodhe, Universidad Autónoma de Tamaulipas, Reynosa 88779, Mexico.ORCID 0000-0003-0124-531X
Debasish BandyopadhyayDepartment of Chemistry and SEEMS, University of Texas Rio Grande Valley, Edinburg, TX 78539, USA.ORCID 0000-0002-2726-5127
Carlos Gaona-LopezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.
Eyra Ortiz-PérezLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0003-3800-0228
Benjamín Nogueda-TorresEscuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México 11340, Mexico.
Esther Ramírez-MorenoEscuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Ciudad de México 07320, Mexico.
Gildardo RiveraLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0000-0001-9842-4167
Instituto Politécnico Nacional · MXAutonomous University of Tamaulipas · MXThe University of Texas Rio Grande Valley · US

Funding

Secretaria de Investigacion y Posgrado del Instituto Politecnico Nacional 20220935
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Trypanocidal AgentsTrypanosoma cruziAnimalsBenzimidazolesHumansLigandsMammalsMolecular Docking SimulationTriose-Phosphate IsomeraseBenzimidazolesLigandsTriose-Phosphate IsomeraseTrypanocidal Agentsinhibitorsmolecular dockingmolecular dynamicstriosephosphate isomeraseTrypanosoma cruzi

Identifiers

PMID36077439
PMCPMC9456061
OpenAlexW4294740761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.