Evidence map›Paper›PMID 36077432›Full record

ArticleInternational journal of molecular sciences2022

Cryptotanshinone Alleviates Oxidative Stress and Reduces the Level of Abnormally Aggregated Protein in

Wen-Bo Cui, Zong-Ping Zhang, Xue Bai, Shan-Shan Wang, Xiao-Han Chen, Xu Liu, Pan-Jie Su, De-Juan Zhi, Dong-Qing Fei, Zhan-Xin Zhang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Components in SLPE Alleviate AD Model Nematodes by Up-Regulating GeneInternational journal of molecular sciences · 2024
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Wen-Bo CuiSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-5953-0124
Zong-Ping ZhangSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Xue BaiSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Shan-Shan WangSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Xiao-Han ChenSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Xu LiuSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Pan-Jie SuSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
De-Juan ZhiSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Dong-Qing FeiSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-5332-8347
Zhan-Xin ZhangSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-7892-9851
Dong-Sheng WangSchool of Pharmacy, State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, China.
Lanzhou University · CN

Funding

National Natural Science Foundation of China 31670350National Natural Science Foundation of China 31870324Natural Science Foundation of Gansu Province, China 21JR7RA444Natural Science Foundation of Gansu Province, China 21JR7RA477
6 · The paper itself

Abstract

Alzheimer's disease (AD) is one of the leading causes of dementia. As the first common neurodegenerative disease, there are no effective drugs that can reverse the progression. The present study is to report the anti-AD effect of cryptotanshinone (CTS), a natural product isolated from

Indexed as

Alzheimer DiseaseCaenorhabditis elegans ProteinsNeurodegenerative DiseasesAmyloid beta-PeptidesAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansDisease Models, AnimalOxidative StressPhenanthrenesReactive Oxygen SpeciesAmyloid beta-PeptidesCaenorhabditis elegans ProteinscryptotanshinonePhenanthrenesReactive Oxygen SpeciesAlzheimer’s diseaseAβCaenorhabditis eleganscryptotanshinoneoxidative stress

Identifiers

PMID36077432
PMCPMC9456502
OpenAlexW4294741523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.