Evidence map›Paper›PMID 36077412›Full record

ReviewInternational journal of molecular sciences2022

TRPV1: A Common Denominator Mediating Antinociceptive and Antiemetic Effects of Cannabinoids.

Kathleen Louis-Gray, Srinivasan Tupal, Louis S Premkumar

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Cannabinoids: Medicine or PoisonBalkan medical journal · 2025
    Article
  9. Review
  10. Review
  11. New cannabidiol structure-related terpeneFuture medicinal chemistry · 2025
    Article
  12. Review
  13. Review
  14. Endocannabinoid signaling in stress, nausea, and vomiting.Neurogastroenterology and motility · 2025
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Kathleen Louis-GrayDepartment of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.
Srinivasan TupalDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.
Louis S PremkumarDepartment of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.
Southern Illinois University School of Medicine · USUniversity of Michigan–Ann Arbor · US

Funding

Foundation for the National Institutes of Health DA028017, R43DK117674
6 · The paper itself

Abstract

The most common medicinal claims for cannabis are relief from chronic pain, stimulation of appetite, and as an antiemetic. However, the mechanisms by which cannabis reduces pain and prevents nausea and vomiting are not fully understood. Among more than 450 constituents in cannabis, the most abundant cannabinoids are Δ

Indexed as

AntiemeticsCannabinoidsTransient Receptor Potential ChannelsAnalgesicsHumansNauseaPainSolitary NucleusTRPV Cation ChannelsVomitingAnalgesicsAntiemeticsCannabinoidsTransient Receptor Potential ChannelsTRPV1 protein, humanTRPV Cation Channelsantinociception and antiemesiscannabidiolcannabinoidsresiniferatoxinTRPV1Δ9-tetrahydrocannabinol

Identifiers

PMID36077412
PMCPMC9456209
OpenAlexW4294739377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.