Evidence map›Paper›PMID 36077293›Full record

ArticleInternational journal of molecular sciences2022

Pneumonia and Related Conditions in Critically Ill Patients-Insights from Basic and Experimental Studies.

Darya A Kashatnikova, Maryam B Khadzhieva, Dmitry S Kolobkov, Olesya B Belopolskaya, Tamara V Smelaya, Alesya S Gracheva, Ekaterina V Kalinina, Sergey S Larin, Artem N Kuzovlev, Lyubov E Salnikova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Darya A KashatnikovaThe Laboratory of Ecological Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.
Maryam B KhadzhievaThe Laboratory of Ecological Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.
Dmitry S KolobkovThe Laboratory of Ecological Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0003-4225-2057
Olesya B BelopolskayaThe Resource Center "Bio-Bank Center", Research Park of St. Petersburg State University, St. Petersburg 199034, Russia.ORCID 0000-0003-2002-4192
Tamara V SmelayaThe Laboratory of Clinical Pathophysiology of Critical Conditions, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow 107031, Russia.
Alesya S GrachevaThe Laboratory of Ecological Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.ORCID 0000-0003-1361-6085
Ekaterina V KalininaThe Laboratory of Molecular Immunology, Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 117198, Russia.
Sergey S LarinThe Laboratory of Molecular Immunology, Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology, Moscow 117198, Russia.ORCID 0000-0002-2128-0078
Artem N KuzovlevThe Laboratory of Clinical Pathophysiology of Critical Conditions, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow 107031, Russia.
Lyubov E SalnikovaThe Laboratory of Ecological Genetics, Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 119991, Russia.
V.A. Negovsky Scientific Research Institute of General Reanimatology · RUDmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology · RUVavilov Institute of General Genetics · RU

Funding

State assignment of the Ministry of Education and Science of Russia No. 0112-2019-0002 and No. FGWS-2022-0001
6 · The paper itself

Abstract

Pneumonia is an acute infectious disease with high morbidity and mortality rates. Pneumonia's development, severity and outcome depend on age, comorbidities and the host immune response. In this study, we combined theoretical and experimental investigations to characterize pneumonia and its comorbidities as well as to assess the host immune response measured by TREC/KREC levels in patients with pneumonia. The theoretical study was carried out using the Columbia Open Health Data (COHD) resource, which provides access to clinical concept prevalence and co-occurrence from electronic health records. The experimental study included TREC/KREC assays in young adults (18-40 years) with community-acquired (CAP) (

Indexed as

PneumoniaRespiratory Distress SyndromeSepsisCritical IllnessHumansIntensive Care UnitsYoung Adultacute respiratory distress syndrome (ARDS)Columbia Open Health Data (COHD)comorbiditiespneumoniasepsisTREC/KREC

Identifiers

PMID36077293
PMCPMC9456259
OpenAlexW4294308195

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.