Evidence map›Paper›PMID 36077282›Full record

ArticleInternational journal of molecular sciences2022

Subgingival Microbiome in Rheumatoid Arthritis Patients with Periodontitis.

Yi-Jing Chen, Wei-Chun Hung, Yu-Hsiang Chou, Chern-Hsiung Lai, Po Peng, Pei-Syuan Jhou, Min-Ru Tsai, Jim Jinn-Chyuan Sheu, Jeng-Hsien Yen

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
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  11. Article
  12. Article
  13. Antibodies againstFrontiers in immunology · 2023
    Article
  14. A modified method for constructing experimental rat periodontitis model.Frontiers in bioengineering and biotechnology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yi-Jing ChenDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0003-3870-6300
Wei-Chun HungDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Yu-Hsiang ChouDivision of Periodontics, Department of Dentistry, Kaohsiung Medical University Hospital, Kaohsiung 807377, Taiwan.ORCID 0000-0002-3265-0361
Chern-Hsiung LaiSchool of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Po PengDepartment of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.ORCID 0000-0003-3640-9070
Pei-Syuan JhouDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Min-Ru TsaiDepartment of Microbiology and Immunology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807378, Taiwan.
Jim Jinn-Chyuan SheuInstitute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung 804201, Taiwan.
Jeng-Hsien YenDivision of Rheumatology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807377, Taiwan.ORCID 0000-0002-1291-1739
Kaohsiung Medical University · TWNational Sun Yat-sen University · TW

Funding

Kaohsiung Medical University Hospital KMUH 109-9R21Ministry of Science and Technology, Taiwan MOST 111-2314-B-037-084NSYSU-KMU JOINT RESEARCH PROJECT NSYSUKMU 107-P012
6 · The paper itself

Abstract

Rheumatoid arthritis (RA) and periodontitis are suggested to be closely linked based on microbial dysbiosis, but limited subgingival bacteria have been proven in the pathogenesis of RA. We enrolled 30 RA patients and 25 controls and divided them into three groups with matched age, gender, and diabetes statuses: group AM (all of the matched participants), group PD (periodontally diseased), and group PH (periodontally healthy). Their subgingival microbial composition was determined by V3-V4 16S rRNA gene sequencing. Significant differences in subgingival microbial clustering between the RA patients and controls were observed in groups AM and PD. Among the taxa enriched in RA,

Indexed as

Arthritis, RheumatoidMicrobiotaPeriodontitisAnti-Citrullinated Protein AntibodiesAutoantibodiesBacteriaHumansRNA, Ribosomal, 16SAnti-Citrullinated Protein AntibodiesAutoantibodiesRNA, Ribosomal, 16Santi-citrullinated protein antibody (ACPA)microbial dysbiosisperiodontitisrheumatoid arthritissubgingival microbiome

Identifiers

PMID36077282
PMCPMC9456296
OpenAlexW4294308101

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.