Evidence map›Paper›PMID 36077268›Full record

ArticleInternational journal of molecular sciences2022

Efficacy of Combination Therapy with Lenvatinib and Radioactive Iodine in Thyroid Cancer Preclinical Model.

Kensuke Suzuki, Hiroshi Iwai, Keita Utsunomiya, Yumiko Kono, Tadashi Watabe, Yoshiki Kobayashi, Dan Van Bui, Shunsuke Sawada, Yasutaka Yun, Akitoshi Mitani and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Kensuke SuzukiDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0003-1659-1549
Hiroshi IwaiDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0003-2646-8173
Keita UtsunomiyaDepartment of Radiology, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Yumiko KonoDepartment of Radiology, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0002-7977-0272
Tadashi WatabeDepartment of Nuclear Medicine and Tracer Kinetics, Graduate School of Medicine, Osaka University, Suita 565-0871, Osaka, Japan.ORCID 0000-0001-8658-2395
Yoshiki KobayashiDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0003-3755-3074
Dan Van BuiDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Shunsuke SawadaDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0002-5856-5835
Yasutaka YunDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0002-6879-6303
Akitoshi MitaniDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Kenta FukuiDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Haruka SakaiDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Hanh Hong ChuDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Nguyen Manh LinhDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Noboru TanigawaDepartment of Radiology, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.
Akira KandaDepartment of Otolaryngology, Head and Neck Surgery, Kansai Medical University, Hirakata 573-1010, Osaka, Japan.ORCID 0000-0001-6324-721X
Kansai Medical University · JPThe University of Osaka · JP

Funding

Funding from the Academic Society for Research in Otolaryngology, Kansai Medical University Not applicableGrants-in-Aid for Scientific Research 20K18269, 20K18297, and 22K16921The research grant D2 from Kansai Medical University Not applicableThe research grant from Osaka Basic Medical Research of Fujii Memorial Association Not applicable
6 · The paper itself

Abstract

Patients with differentiated thyroid cancer (DTC) usually have good prognosis, while those with advanced disease have poor clinical outcomes. This study aimed to investigate the antitumor effects of combination therapy with lenvatinib and

Indexed as

QuinolinesSymportersThyroid NeoplasmsHumansIodine RadioisotopesPhenylurea CompoundsIodine RadioisotopeslenvatinibPhenylurea CompoundsQuinolinesSymporterscombination therapylenvatinibradioactive iodinesodium iodide symporterthyroid cancer

Identifiers

PMID36077268
PMCPMC9456011
OpenAlexW4293773122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.