Evidence map›Paper›PMID 36077225›Full record

ArticleInternational journal of molecular sciences2022

A Lupin (

Guillermo Santos-Sánchez, Eduardo Ponce-España, Juan Carlos López, Nuria Álvarez-Sánchez, Ana Isabel Álvarez-López, Justo Pedroche, Francisco Millán, María Carmen Millán-Linares, Patricia Judith Lardone, Ignacio Bejarano and 2 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Guillermo Santos-SánchezInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.ORCID 0000-0001-5790-2302
Eduardo Ponce-EspañaInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.
Juan Carlos LópezDepartamento de Psicología Experimental, Universidad de Sevilla, 41009 Seville, Spain.ORCID 0000-0001-8106-5006
Nuria Álvarez-SánchezInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.ORCID 0000-0002-1313-0440
Ana Isabel Álvarez-LópezInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.
Justo PedrocheDepartment of Food & Health, Instituto de la Grasa, CSIC, Ctra, Utrera Km 1, 41013 Seville, Spain.
Francisco MillánDepartment of Food & Health, Instituto de la Grasa, CSIC, Ctra, Utrera Km 1, 41013 Seville, Spain.ORCID 0000-0001-6309-7629
María Carmen Millán-LinaresDepartamento de Bioquímica Médica y Biología Molecular e Inmunología, Facultad de Medicina, Universidad de Sevilla, 41009 Seville, Spain.ORCID 0000-0002-5661-8366
Patricia Judith LardoneInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.ORCID 0000-0003-1793-3985
Ignacio BejaranoInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.ORCID 0000-0003-3727-3873
Ivan Cruz-ChamorroInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.ORCID 0000-0002-6547-8078
Antonio Carrillo-VicoInstituto de Biomedicina de Sevilla, IBiS (Universidad de Sevilla, HUVR, Junta de Andalucía, CSIC), 41013 Seville, Spain.ORCID 0000-0002-8516-0999
Instituto de Biomedicina de Sevilla · ESInstituto de la Grasa · ESUniversidad de Sevilla · ES

Funding

Consejería de Salud y Familias PC-0111-2016-0111, and PEMP-0085-2020Instituto de Salud Carlos III RD12/0043/0012Ministerio de Educación Cultura y Deporte FPU16/02339Ministry of Economy, Industry and Competitiveness AGL2012-40247-C02-01, and AGL2012-40247-C02-02Regional Government of Andalusia CTS160Regional Government of Andalusia DOC_00587/2020 and PI-0136-2019University of Seville VIPPIT-2020-II.4 and VI PPIT-US
6 · The paper itself

Abstract

Anxiety is the most prevalent psychiatric disorder worldwide, causing a substantial economic burden due to the associated healthcare costs. Given that commercial anxiolytic treatments may cause important side effects and have medical restrictions for prescription and high costs, the search for new natural and safer treatments is gaining attention. Since lupin protein hydrolysate (LPH) has been shown to be safe and exert anti-inflammatory and antioxidant effects, key risk factors for the anxiety process and memory impairment, we evaluated in this study the potential effects of LPH on anxiety and spatial memory in a Western diet (WD)-induced anxiety model in ApoE

Indexed as

Anti-Anxiety AgentsAnimalsAnxietyApolipoproteins EBehavior, AnimalDiet, WesternHumansMaze LearningMiceProtein HydrolysatesAnti-Anxiety AgentsApolipoproteins EProtein HydrolysatesanxietyApoE−/−functional foodslupinpeptidespeptidomicsprotein hydrolysates

Identifiers

PMID36077225
PMCPMC9456304
OpenAlexW4293724000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.