Evidence map›Paper›PMID 36077054›Full record

ArticleInternational journal of molecular sciences2022

RNA Editing Enzyme ADAR1 Regulates METTL3 in an Editing Dependent Manner to Promote Breast Cancer Progression via METTL3/ARHGAP5/YTHDF1 Axis.

Yi Li, Ning-Xi Wang, Chuan Yin, Shan-Shan Jiang, Jia-Chu Li, Sheng-Yong Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
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  9. Global analysis by LC-MS/MS ofRNA (New York, N.Y.) · 2025
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  19. The role of ADAR1 through and beyond its editing activity in cancer.Cell communication and signaling : CCS · 2024
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yi LiDepartment of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.ORCID 0000-0002-4772-0748
Ning-Xi WangDepartment of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Chuan YinDepartment of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Shan-Shan JiangDepartment of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.
Jia-Chu LiDepartment of Oncology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China.
Sheng-Yong YangDepartment of Biochemistry and Molecular Biology, Molecular Medicine and Cancer Research Center, College of Basic Medicine, Chongqing Medical University, Chongqing 400016, China.ORCID 0000-0001-7312-0255
Chongqing Medical University · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CN

Funding

National Natural Science Foundation of China 81872444;81602159The Natural Science Foundation of Chongqing cstc2021jcyj-msxmX0238 , cstc2016jcyjA0054The Science and Technology Planning Project of Yuzhong District, Chongqing City Grant 20170109
6 · The paper itself

Abstract

A-to-I RNA editing and m

Indexed as

Breast NeoplasmsMicroRNAsAdenosine DeaminaseFemaleGTPase-Activating ProteinsHumansMethyltransferasesRNA-Binding ProteinsRNA EditingRNA, MessengerADAR protein, humanAdenosine DeaminaseARHGAP5 protein, humanGTPase-Activating ProteinsMethyltransferasesMETTL3 protein, humanMicroRNAsMIRN532 microRNA, humanRNA-Binding ProteinsRNA, MessengerYTHDF1 protein, humanADAR1ARHGAP5breast cancerMETTL3YTHDF1

Identifiers

PMID36077054
PMCPMC9456332
OpenAlexW4293217715

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.